PLCD1 抗体 (AA 14-549) (Biotin)
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Quick Overview for PLCD1 抗体 (AA 14-549) (Biotin) (ABIN8022158)
抗原
See all PLCD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 14-549
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原理
- Anti-PLCD1 Antibody Biotin Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Human PLCD1 shares 92.2%,92.5% amino acid (aa) sequence identity with mouse,rat PLCD1,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PLCD1 recombinant protein (Position: Q14-R549). Human PLCD1 shares 92.2% and 92.5% amino acid (aa) sequence identity with mouse and rat PLCD1, respectively.
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亚型
- IgG
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- PLCD1 (phospholipase C, delta 1 (PLCD1))
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别名
- PLCD1
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背景
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Background: This gene encodes a member of the phospholipase C family. Phospholipase C isozymes play critical roles in intracellular signal transduction by catalyzing the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers diacylglycerol (DAG) and inositol triphosphate (IP3). The encoded protein functions as a tumor suppressor in several types of cancer, and mutations in this gene are a cause of hereditary leukonychia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene Full Name: phospholipase C delta 1
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基因ID
- 5333
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UniProt
- P51178
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途径
- WNT signaling, Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process
抗原
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