PDE12 抗体 (AA 36-607)
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北京 101111
Quick Overview for PDE12 抗体 (AA 36-607) (ABIN8021409)
抗原
See all PDE12 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 36-607
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原理
- Anti-PDE12 Antibody
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交叉反应 （详细）
- No cross reactivity with other proteins.
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预测反应
- Human PDE12 shares 89.9%,91.3% amino acid (aa) sequence identity with mouse,rat PDE12,respectively.
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产品特性
- Anti-PDE12 Antibody. Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PDE12 recombinant protein (Position: E36-K607). Human PDE12 shares 89.9% and 91.3% amino acid (aa) sequence identity with mouse and rat PDE12, respectively.
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亚型
- IgG
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anti-Phosphodiesterase 12 (PDE12) (AA 17-300) antibody
PDE12 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Phosphodiesterase 12 (PDE12) (AA 362-390), (C-Term) antibodyPDE12 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB27765 unconjugated
anti-Phosphodiesterase 12 (PDE12) (AA 1-575) antibodyPDE12 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Phosphodiesterase 12 (PDE12) (AA 559-609) antibodyPDE12 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphodiesterase 12 (PDE12) (C-Term) antibodyPDE12 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 犬, 兔, 猴, Pig, Bat, 小鸡, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphodiesterase 12 (PDE12) (AA 290-602) antibodyPDE12 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Phosphodiesterase 12 (PDE12) (AA 369-398), (C-Term) antibodyPDE12 适用: 人 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- PDE12 (Phosphodiesterase 12 (PDE12))
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别名
- PDE12
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背景
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Background: PDE12 is an enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. This enzyme degraded triphosphorylated 2-5A to produce AMP and ATP. It also cleaves 3',5'-phosphodiester bond of oligoadenylates and plays a role as a negative regulator of the The 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons (IFNs). Suppression of this enzyme induces reduction of viral replication in Hela cells, thus counteracting the antiviral pathway probably by inhibiting the 2-5A system.
Gene Full Name: phosphodiesterase 12
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分子量
- 70 kDa
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基因ID
- 201626
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UniProt
- Q6L8Q7
抗原
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