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PDE12 抗体 (AA 559-609)

PDE12 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7449244
发货至: 中国
  • 抗原 See all PDE12 抗体
    PDE12 (Phosphodiesterase 12 (PDE12))
    抗原表位
    • 10
    • 8
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 559-609
    适用
    • 25
    • 9
    • 7
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 27
    • 1
    克隆类型
    • 28
    多克隆
    标记
    • 15
    • 4
    • 3
    • 2
    • 2
    • 2
    This PDE12 antibody is un-conjugated
    应用范围
    • 28
    • 17
    • 14
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    原理
    Rabbit anti-PDE12 Antibody, Affinity Purified
    预测反应
    Mouse,Rat,Bovine
    纯化方法
    Affinity Purified
    免疫原
    Between AA 559 and 609
    亚型
    IgG
    Top Product
    Discover our top product PDE12 Primary Antibody
  • 应用备注
    1:2,000 - 1:10,000
    限制
    仅限研究用
  • 浓度
    1000 μg/mL
    缓冲液
    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    有效期
    12 months
  • 抗原
    PDE12 (Phosphodiesterase 12 (PDE12))
    别名
    PDE12 (PDE12 产品)
    别名
    2'-PDE antibody, E430028B21Rik antibody, LRRGT00074 antibody, RGD1310975 antibody, phosphodiesterase 12 S homeolog antibody, phosphodiesterase 12 antibody, pde12.S antibody, PDE12 antibody, pde12 antibody, Pde12 antibody
    背景
    Background: PDE12 is an enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. This enzyme degraded triphosphorylated 2-5A to produce AMP and ATP. It also cleaves 3',5'-phosphodiester bond of oligoadenylates and plays a role as a negative regulator of the The 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons (IFNs). Suppression of this enzyme induces reduction of viral replication in Hela cells, thus counteracting the antiviral pathway probably by inhibiting the 2-5A system [taken from the Universal Protein Resource (UniProt) Q6L8Q7].
    基因ID
    201626
    UniProt
    Q6L8Q7
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