PGC 抗体 (AA 145-356)
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北京 101111
Quick Overview for PGC 抗体 (AA 145-356) (ABIN8020083)
抗原
See all PGC 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 145-356
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原理
- Anti-PGC Antibody
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交叉反应 （详细）
- No cross reactivity with other proteins.
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预测反应
- Human PGC shares 69.5%,70% amino acid (aa) sequence identity with mouse,rat PGC,respectively.
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产品特性
- Anti-PGC Antibody. Tested in ELISA, IF, IHC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PGC recombinant protein (Position: Y145-N356). Human PGC shares 69.5% and 70% amino acid (aa) sequence identity with mouse and rat PGC, respectively.
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亚型
- IgG
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anti-Pepsinogen C (PGC) (AA 100-200) antibody
PGC 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pepsinogen C (PGC) (AA 17-392) antibodyPGC 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pepsinogen C (PGC) (Internal Region) antibodyPGC 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Pepsinogen C (PGC) (AA 1-388) antibodyPGC 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Pepsinogen C (PGC) (AA 1-388) antibodyPGC 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Pepsinogen C (PGC) (AA 61-388) antibodyPGC 适用: 人 WB, IHC, IP, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Pepsinogen C (PGC) (AA 21-120) antibodyPGC 适用: 人 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Pepsinogen C (PGC) (pSer15) antibodyPGC 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Pepsinogen C (PGC) antibodyPGC 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 1G1H3 unconjugated
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应用备注
- Western blot, 0.25-0.5 μg/mL, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat Immunofluorescence, 5 μg/mL, Human, Rat Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- PGC (Pepsinogen C (PGC))
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别名
- PGC
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背景
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Background: Progastricsin also known as pepsinogen C or pepsinogen II is a pepsinogen precursor of the enzyme gastricsin that in humans is encoded by the PGC gene. This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1.
Gene Full Name: progastricsin
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分子量
- 38 kDa
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基因ID
- 5225
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UniProt
- P20142
抗原
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