Patched 2 抗体 (Middle Region) (APC)
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北京 101111
Quick Overview for Patched 2 抗体 (Middle Region) (APC) (ABIN8019765)
抗原
See all Patched 2 (PTCH2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- Anti-PTCH2 Antibody APC Conjugated
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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预测反应
- identical to the related mouse sequence.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human PTCH2, identical to the related mouse sequence.
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亚型
- IgG
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anti-Patched 2 (PTCH2) (AA 793-951) antibody
PTCH2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Patched 2 (PTCH2) (AA 362-411) antibodyPTCH2 适用: 人, Cow, 犬, 马, 兔, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- Patched 2 (PTCH2)
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别名
- PTCH2
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背景
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Background: PTCH2 (patched 2), also known as PTC2, encodes a 1.203-amino acid putative transmembrane protein that is highly homologous to the PTCH product. The Patched-hedgehog signaling pathway is involved in establishing segment polarity and the anterior-posterior orientation of a number of developing appendages. The pathway is conserved from fly to vertebrates and has been implicated in a number of human neoplasms and developmental syndromes. Mutations in the human Patched gene are the basis of the nevoid basal cell carcinoma syndrome. With age, homozygous mutant male mice developed skin lesions consisting of alopecia and epidermal hyperplasia, suggesting a role forPtch2in adult epidermal homeostasis via Shh signaling.
Gene Full Name: patched 2
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基因ID
- 8643
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UniProt
- Q9Y6C5
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途径
- Hedgehog Signaling
抗原
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