HRPT2 抗体 (AA 119-520)
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Quick Overview for HRPT2 抗体 (AA 119-520) (ABIN8019460)
抗原
See all HRPT2 (CDC73) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 119-520
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原理
- Anti-HRPT2/CDC73 Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Human HRPT2 shares 100%,99.8% amino acid (aa) sequence identity with mouse,rat HRPT2,respectively.
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产品特性
- Anti-HRPT2/CDC73 Antibody. Tested in WB applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human HRPT2 recombinant protein (Position: Q119-R520). Human HRPT2 shares 100% and 99.8% amino acid (aa) sequence identity with mouse and rat HRPT2, respectively.
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亚型
- IgG
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应用备注
- Western blot, 0.1-0.5 μg/mL, Human
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- HRPT2 (CDC73) (Parafibromin (CDC73))
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别名
- CDC73
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背景
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Background: Cell division cycle 73, also known as HRPT2, is a protein which in humans is encoded by the CDC73 gene. This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. And this protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.
Gene Full Name: cell division cycle 73
Sequence Similarities: Belongs to the CDC73 family.
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分子量
- 61 kDa
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基因ID
- 79577
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UniProt
- Q6P1J9
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途径
- Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance
抗原
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