OTUB1 抗体 (AA 10-271) (HRP)
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Quick Overview for OTUB1 抗体 (AA 10-271) (HRP) (ABIN8018662)
抗原
See all OTUB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 10-271
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原理
- Anti-OTUB1 Antibody HRP Conjugated
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交叉反应 (详细)
- No cross reactivity with other proteins.
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预测反应
- Human OTUB1 shares 99.6% amino acid (aa) sequence identity with both mouse,rat OTUB1.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human OTUB1 recombinant protein (Position: K10-K271). Human OTUB1 shares 99.6% amino acid (aa) sequence identity with both mouse and rat OTUB1.
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亚型
- IgG
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- OTUB1 (OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1))
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别名
- OTUB1
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背景
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Background: Ubiquitin thioesterase OTUB1 also known as otubain-1 is an enzyme that in humans is encoded by the OTUB1 gene. The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants.
Gene Full Name: OTU deubiquitinase, ubiquitin aldehyde binding 1
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基因ID
- 55611
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UniProt
- Q96FW1
抗原
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