Osteocalcin 抗体 (AA 50-99)
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Quick Overview for Osteocalcin 抗体 (AA 50-99) (ABIN8018523)
抗原
See all Osteocalcin (BGLAP) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 50-99
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原理
- Anti-Osteocalcin/BGLAP Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- coli-derived rat Osteocalcin recombinant protein (Position: Y50-V99). Rat Osteocalcin shares 80.9%,68.9% amino acid (aa) sequence identity with human,mouse Osteocalcin,respectively.
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产品特性
- Anti-Osteocalcin/BGLAP Antibody. Tested in Flow Cytometry, IHC applications. This antibody reacts with Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived rat Osteocalcin recombinant protein (Position: Y50-V99). Rat Osteocalcin shares 80.9% and 68.9% amino acid (aa) sequence identity with human and mouse Osteocalcin, respectively.
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亚型
- IgG
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应用备注
- Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Rat Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Rat
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- Osteocalcin (BGLAP)
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别名
- Bglap
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背景
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Background: Osteocalcin, also known as bone gamma-carboxyglutamic acid-containing protein (BGLAP), is a noncollagenous protein found in bone and dentin. In humans, the osteocalcin is encoded by the BGLAP gene. Its receptor is GPRC6A. It is mapped to 1q22. Osteocalcin may play a role in the body's metabolic regulation and is pro-osteoblastic, or bone-building. It acts as a hormone in the body, causing beta cellsin the pancreas to release more insulin, and at the same time ing fat cells to release the hormone adiponectin, which increases sensitivity to insulin. Also, it may play a role in male fertility. And it is found that picomolar amounts of osteocalcin affected insulin secretion and beta-cell proliferation.
Gene Full Name: bone gamma-carboxyglutamate protein
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分子量
- 29 kDa, 60 kDa
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基因ID
- 25295
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UniProt
- P04640
抗原
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