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Osteocalcin 抗体 (AA 50-95)

The 兔 多克隆 anti-Osteocalcin antibody (ABIN8018512) specifically detects Osteocalcin in IHC. The antibody is reactive with 小鼠 samples.
产品编号 ABIN8018512
发货至: 中国
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for Osteocalcin 抗体 (AA 50-95) (ABIN8018512)

抗原

See all Osteocalcin (BGLAP) 抗体
Osteocalcin (BGLAP)

适用

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小鼠

宿主

  • 120
  • 36
  • 2
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克隆类型

  • 114
  • 47
多克隆

标记

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This Osteocalcin antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)

质量等级

Carrier-free
  • 抗原表位

    • 19
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    AA 50-95

    原理

    Anti-Osteocalcin/BGLAP Antibody

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    coli-derived mouse Osteocalcin recombinant protein (Position: Y50-I95). Mouse Osteocalcin shares 69%,68.9% amino acid (aa) sequence identity with human,rat Osteocalcin,respectively.

    产品特性

    Anti-Osteocalcin/BGLAP Antibody. Tested in IHC applications. This antibody reacts with Mouse.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived mouse Osteocalcin recombinant protein (Position: Y50-I95). Mouse Osteocalcin shares 69% and 68.9% amino acid (aa) sequence identity with human and rat Osteocalcin, respectively.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Osteocalcin (BGLAP)

    别名

    Bglap

    背景

    Background: Osteocalcin, also known as bone gamma-carboxyglutamic acid-containing protein (BGLAP), is a noncollagenous protein found in bone and dentin. In humans, the osteocalcin is encoded by the BGLAP gene. Its receptor is GPRC6A. It is mapped to 1q22. Osteocalcin may play a role in the body's metabolic regulation and is pro-osteoblastic, or bone-building. It acts as a hormone in the body, causing beta cellsin the pancreas to release more insulin, and at the same time ing fat cells to release the hormone adiponectin, which increases sensitivity to insulin. Also, it may play a role in male fertility. And it is found that picomolar amounts of osteocalcin affected insulin secretion and beta-cell proliferation.

    Gene Full Name: bone gamma carboxyglutamate protein

    分子量

    29 kDa, 60 kDa

    基因ID

    12096

    UniProt

    P86546
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