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Osteocalcin 抗体 (AA 52-100) (HRP)

The HRP-conjugated 兔 多克隆 anti-Osteocalcin antibody (ABIN8018497) specifically detects Osteocalcin in IHC, WB 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN8018497
发货至: 中国
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Quick Overview for Osteocalcin 抗体 (AA 52-100) (HRP) (ABIN8018497)

抗原

See all Osteocalcin (BGLAP) 抗体
Osteocalcin (BGLAP)

适用

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宿主

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克隆类型

  • 114
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多克隆

标记

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This Osteocalcin antibody is conjugated to HRP

应用范围

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Immunohistochemistry (IHC), Western Blotting (WB), ELISA
  • 抗原表位

    • 18
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    AA 52-100

    原理

    Anti-Osteocalcin/BGLAP Antibody HRP Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    coli-derived human Osteocalcin recombinant protein (Position: Y52-V100). Human Osteocalcin shares 69%,80.9% amino acid (aa) sequence identity with mouse,rat Osteocalcin,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human Osteocalcin recombinant protein (Position: Y52-V100). Human Osteocalcin shares 69% and 80.9% amino acid (aa) sequence identity with mouse and rat Osteocalcin, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    Osteocalcin (BGLAP)

    别名

    BGLAP

    背景

    Background: Osteocalcin, also known as bone gamma-carboxyglutamic acid-containing protein (BGLAP), is a noncollagenous protein found in bone and dentin. In humans, the osteocalcin is encoded by the BGLAP gene. Its receptor is GPRC6A. It is mapped to 1q22. Osteocalcin may play a role in the body's metabolic regulation and is pro-osteoblastic, or bone-building. It acts as a hormone in the body, causing beta cellsin the pancreas to release more insulin, and at the same time ing fat cells to release the hormone adiponectin, which increases sensitivity to insulin. Also, it may play a role in male fertility. And it is found that picomolar amounts of osteocalcin affected insulin secretion and beta-cell proliferation.

    Gene Full Name: bone gamma-carboxyglutamate protein

    基因ID

    632

    UniProt

    P02818
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