OPTN 抗体 (AA 241-577)
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北京 101111
Quick Overview for OPTN 抗体 (AA 241-577) (ABIN8018267)
抗原
See all OPTN 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 241-577
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原理
- Anti-Optineurin/OPTN Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- Human Optineurin shares 82% amino acid (aa) sequence identity with both mouse,rat Optineurin.
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产品特性
- Anti-Optineurin/OPTN Antibody. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Optineurin recombinant protein (Position: R241-I577). Human Optineurin shares 82% amino acid (aa) sequence identity with both mouse and rat Optineurin.
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亚型
- IgG
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anti-Optineurin (OPTN) antibody
KD Validated OPTN 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB4715 unconjugated Recombinant Antibody
anti-Optineurin (OPTN) (AA 241-577) antibodyOPTN 适用: 人, 小鼠, 大鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Optineurin (OPTN) (AA 341-440) antibodyOPTN 适用: 人, 小鼠 WB, ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Optineurin (OPTN) (AA 1-300) antibodyOPTN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Optineurin (OPTN) (AA 1-577) antibodyOPTN 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Optineurin (OPTN) antibodyOPTN 适用: 人 WB, IP, ICC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Optineurin (OPTN) (AA 1-577) antibodyOPTN 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Optineurin (OPTN) (AA 1-577) antibodyOPTN 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Optineurin (OPTN) (AA 559-575) antibodyOPTN 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Optineurin (OPTN) (AA 575-591) antibodyOPTN 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- OPTN (Optineurin (OPTN))
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别名
- OPTN
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背景
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Background: OPTN is also known as NRP, FIP2 or HYPL. This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.
Gene Full Name: optineurin
Sequence Similarities: Belongs to the nuclear hormone receptor family. NR3 subfamily.
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分子量
- 75 kDa
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基因ID
- 10133
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UniProt
- Q96CV9
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途径
- M Phase
抗原
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