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NAE1 抗体 (AA 181-534)

The 兔 多克隆 anti-NAE1 antibody is suitable to detect NAE1 in samples from 人, 小鼠 和 大鼠. It has been validated for WB.
产品编号 ABIN8014173
发货至: 中国
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Quick Overview for NAE1 抗体 (AA 181-534) (ABIN8014173)

抗原

See all NAE1 抗体
NAE1 (NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

  • 67
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多克隆

标记

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This NAE1 antibody is un-conjugated

应用范围

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Western Blotting (WB)

质量等级

Carrier-free
  • 抗原表位

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    AA 181-534

    原理

    Anti-APPBP1/NAE1 Antibody

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human APPBP1 shares 98% amino acid (aa) sequence identity with mouse APPBP1.

    产品特性

    Anti-APPBP1/NAE1 Antibody. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human APPBP1 recombinant protein (Position: E181-L534). Human APPBP1 shares 98% amino acid (aa) sequence identity with mouse APPBP1.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    NAE1 (NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))

    别名

    NAE1

    背景

    Background: NAE1 is also known as APPBP1. The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.

    Gene Full Name: NEDD8 activating enzyme E1 subunit 1

    分子量

    42 kDa

    基因ID

    8883

    UniProt

    Q13564
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