MPG 抗体 (C-Term) (APC)
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Quick Overview for MPG 抗体 (C-Term) (APC) (ABIN8013180)
抗原
See all MPG 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-MPG Antibody APC Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- different from the related mouse sequence by two amino acids,and from related rat sequence by one amino acid.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human MPG, different from the related mouse sequence by two amino acids, and from related rat sequence by one amino acid.
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亚型
- IgG
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anti-N-Methylpurine-DNA Glycosylase (MPG) (AA 1-90) antibody
MPG 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1E10 unconjugated
anti-N-Methylpurine-DNA Glycosylase (MPG) (AA 221-296) antibodyMPG 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-N-Methylpurine-DNA Glycosylase (MPG) (AA 1-90) antibodyMPG 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1G6 unconjugated
anti-N-Methylpurine-DNA Glycosylase (MPG) (C-Term) antibodyVerified MPG 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-N-Methylpurine-DNA Glycosylase (MPG) (C-Term) antibodyMPG 适用: 人, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-N-Methylpurine-DNA Glycosylase (MPG) (C-Term) antibodyMPG 适用: 人, 大鼠, 小鼠, Cow, 豚鼠, 兔, Hamster, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-N-Methylpurine-DNA Glycosylase (MPG) antibodyMPG 适用: 人 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-N-Methylpurine-DNA Glycosylase (MPG) (C-Term) antibodyMPG 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- MPG (N-Methylpurine-DNA Glycosylase (MPG))
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别名
- MPG
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背景
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Background: MPG (N-methylpurine-DNA glycosylase) also known as MDG, 3-METHYLADENINE DNA GLYCOSYLASE, 3MeAde DNA GLYCOSYLASE, AAG or APNG. The MPG gene is mapped to human chromosome 16 by analysis of a panel of DNAs from mouse/human and hamster/human hybrid cell lines. The MPG gene was expressed in all cell lines and tissues examined, but was found at particularly high levels in a colon adenocarcinoma cell line (HT29). The completely characterized human MPG gene was found to span 7 to 8 kb of genomic DNA and to be localized 75 kb upstream of the embryonic zeta-globin gene. To assess the contribution of Apng to the repair of several mutagenic lesions in vivo, Hang et al. (1997) biochemically analyzed cell-free extracts of tissues from mice with a targeted deletion of the Apng gene. Following treatment with DNA-methylating agents, increased persistence of 7-methylguanine (meG) was found in liver sections of APNG knockout mice in comparison with wildtype mice, demonstrating an in vivo phenotype for the APNG-null animals.
Gene Full Name: N-methylpurine DNA glycosylase
Sequence Similarities: Belongs to the DNA glycosylase MPG family.
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基因ID
- 4350
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UniProt
- P29372
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途径
- DNA Damage Repair
抗原
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