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MSH6 抗体 (AA 357-388)

The 兔 多克隆 anti-MSH6 antibody (ABIN8012224) specifically detects MSH6 in WB, IF, ELISA, FACS 和 ICC. The antibody is reactive with 人 samples.
产品编号 ABIN8012224
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MSH6 抗体 (AA 357-388) (ABIN8012224)

抗原

See all MSH6 抗体
MSH6 (MutS Homolog 6 (E. Coli) (MSH6))

适用

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宿主

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克隆类型

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多克隆

标记

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This MSH6 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

质量等级

Carrier-free
  • 抗原表位

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    AA 357-388

    原理

    Anti-MSH6 Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-MSH6 Antibody. Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human MSH6 recombinant protein (Position: D357-H388).

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.25 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    MSH6 (MutS Homolog 6 (E. Coli) (MSH6))

    别名

    MSH6

    背景

    Background: MSH6 or mutS homolog 6 is a gene that codes for DNA mismatch repair protein Msh6 in the budding yeast Saccharomyces cerevisiae. This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a biional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described.

    Gene Full Name: mutS homolog 6

    分子量

    160 kDa

    基因ID

    2956

    UniProt

    P52701

    途径

    DNA Damage Repair, Chromatin Binding, Production of Molecular Mediator of Immune Response
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