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MBNL1 抗体 (AA 89-388) (HRP)

The 兔 多克隆 anti-MBNL1 antibody is suitable to detect MBNL1 in samples from 人, 小鼠, 大鼠 和 猴. It has been validated for WB, ELISA 和 IHC.
产品编号 ABIN8012154
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MBNL1 抗体 (AA 89-388) (HRP) (ABIN8012154)

抗原

See all MBNL1 抗体
MBNL1 (Muscleblind-like Protein 1 (MBNL1))

适用

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人, 小鼠, 大鼠, 猴

宿主

  • 43
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  • 1

克隆类型

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多克隆

标记

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This MBNL1 antibody is conjugated to HRP

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 89-388

    原理

    Anti-MBNL1 Antibody HRP Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human MBNL1 recombinant protein (Position: Q89-M388).

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    MBNL1 (Muscleblind-like Protein 1 (MBNL1))

    别名

    MBNL1

    背景

    Background: Muscleblind-like (Drosophila), also known as MBNL1, is a protein that in humans is encoded by the MBNL1 gene. It is mapped to 3q25.1-q25.2. This gene encodes a member of the muscleblind protein family which was initially described in Drosophila melanogaster. The encoded protein is a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Mice lacking this gene exhibited muscle abnormalities and cataracts. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. The different isoforms are thought to have different binding specificities and/or splicing activities.

    Gene Full Name: muscleblind like splicing regulator 1

    基因ID

    4154

    UniProt

    Q9NR56

    途径

    Ribonucleoprotein Complex Subunit Organization
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