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- 抗原 See all MBNL1 抗体
- MBNL1 (Muscleblind-like Protein 1 (MBNL1))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MBNL1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 特异性
- MBNL1 Antibody detects endogenous levels of total MBNL1.
- 预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human MBNL1, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product MBNL1 Primary Antibody
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anti-Muscleblind-like Protein 1 (MBNL1) (AA 1-382) antibody
MBNL1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3E7 unconjugated
anti-Muscleblind-like Protein 1 (MBNL1) antibodyMBNL1 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Muscleblind-like Protein 1 (MBNL1) (AA 1-383) antibodyMBNL1 适用: 人 WB, ELISA, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 3E7 unconjugated
anti-Muscleblind-like Protein 1 (MBNL1) (Middle Region) antibodyMBNL1 适用: 人, 大鼠, 小鼠, 犬, 兔, 马, Pig, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Muscleblind-like Protein 1 (MBNL1) (C-Term) antibodyMBNL1 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Muscleblind-like Protein 1 (MBNL1) (AA 1-382) antibodyMBNL1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Muscleblind-like Protein 1 (MBNL1) (AA 211-260) antibodyMBNL1 适用: 人, 大鼠, 犬, 兔, 马, Pig, 斑马鱼, 猴, Bat, 小鸡, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Muscleblind-like Protein 1 (MBNL1) (AA 1-343) antibodyMBNL1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D11 unconjugated
anti-Muscleblind-like Protein 1 (MBNL1) (AA 211-260) antibodyMBNL1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Muscleblind-like Protein 1 (MBNL1) (AA 1-382) antibodyMBNL1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- MBNL1 (Muscleblind-like Protein 1 (MBNL1))
- 别名
- MBNL1 (MBNL1 产品)
- 别名
- MBNL1 antibody, zgc:153954 antibody, Mbnl antibody, mKIAA0428 antibody, EXP antibody, EXP35 antibody, EXP40 antibody, EXP42 antibody, MBNL antibody, muscleblind like splicing regulator 1 antibody, muscleblind-like splicing regulator 1 antibody, muscleblind like splicing factor 1 antibody, MBNL1 antibody, mbnl1 antibody, Mbnl1 antibody
- 背景
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Description: Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. Regulates the TNNT2 exon 5 skipping through competition with U2AF2. Inhibits the formation of the spliceosome A complex on intron 4 of TNNT2 pre-mRNA. Binds to the stem-loop structure within the polypyrimidine tract of TNNT2 intron 4 during spliceosome assembly. Binds to the 5'-YGCU(U/G)Y-3'consensus sequence. Binds to the IR RNA. Binds to expanded CUG repeat RNA, which folds into a hairpin structure containing GC base pairs and bulged, unpaired U residues.
Gene: MBNL1
- 分子量
- 42 kDa
- 基因ID
- 4154
- UniProt
- Q9NR56
- 途径
- Ribonucleoprotein Complex Subunit Organization
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