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MUS81 抗体 (AA 6-545) (Fluoro550)

The Fluoro550-conjugated 兔 多克隆 anti-MUS81 antibody (ABIN8012074) specifically detects MUS81 in FACS. The antibody is reactive with 人 和 大鼠 samples.
产品编号 ABIN8012074
发货至: 中国
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Quick Overview for MUS81 抗体 (AA 6-545) (Fluoro550) (ABIN8012074)

抗原

See all MUS81 抗体
MUS81 (MUS81 Endonuclease Homolog (MUS81))

适用

  • 41
  • 28
  • 19
  • 2
  • 2
  • 1
人, 大鼠

宿主

  • 40
  • 1

克隆类型

  • 41
多克隆

标记

  • 18
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
This MUS81 antibody is conjugated to Fluoro550

应用范围

  • 19
  • 17
  • 15
  • 8
  • 5
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 13
    • 11
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 6-545

    原理

    Anti-MUS81 Antibody Fluoro550 Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human MUS81 recombinant protein (Position: R6-C545).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    MUS81 (MUS81 Endonuclease Homolog (MUS81))

    别名

    MUS81

    背景

    Background: Crossover junction endonuclease MUS81 is an enzyme that in humans is encoded by the MUS81 gene. This gene encodes a structure-specific endonuclease which belongs to the XPF/MUS81 endonuclease family and plays a critical role in the resolution of recombination intermediates during DNA repair after inter-strand cross-links, replication fork collapse, and DNA double-strand breaks. The encoded protein associates with one of two closely related essential meiotic endonuclease proteins (EME1 or EME2) to form a complex that processes DNA secondary structures. It contains an N-terminal DEAH helicase domain, an excision repair cross complementation group 4 (ERCC4) endonuclease domain, and two tandem C-terminal helix-hairpin-helix domains. Mice with a homozygous knockout of the orthologous gene have significant meiotic defects including the failure to repair a subset of DNA double strand breaks.

    Gene Full Name: MUS81 structure-specific endonuclease subunit

    基因ID

    80198

    UniProt

    Q96NY9

    途径

    DNA Damage Repair
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