Menin 抗体 (AA 301-615) (HRP)
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北京 101111
Quick Overview for Menin 抗体 (AA 301-615) (HRP) (ABIN8012044)
抗原
See all Menin (MEN1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 301-615
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原理
- Anti-Menin/MEN1 Antibody HRP Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- Human Menin shares 93%,94% amino acid (aa) sequence identity with mouse,rat Menin,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Menin recombinant protein (Position: P301-L615). Human Menin shares 93% and 94% amino acid (aa) sequence identity with mouse and rat Menin, respectively.
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亚型
- IgG
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anti-Multiple Endocrine Neoplasia 1 (MEN1) (AA 392-554) antibody
MEN1 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 7D3E10 unconjugated
anti-Multiple Endocrine Neoplasia 1 (MEN1) (AA 501-615) antibodyMEN1 适用: 人, 小鼠, 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Multiple Endocrine Neoplasia 1 (MEN1) (AA 219-395) antibodyMEN1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Multiple Endocrine Neoplasia 1 (MEN1) (AA 1-575) antibodyMEN1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Multiple Endocrine Neoplasia 1 (MEN1) (AA 1-575) antibodyMEN1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Multiple Endocrine Neoplasia 1 (MEN1) (Internal Region) antibodyMEN1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Multiple Endocrine Neoplasia 1 (MEN1) (AA 584-615) antibodyMEN1 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB0543 unconjugated
anti-Multiple Endocrine Neoplasia 1 (MEN1) (C-Term) antibodyMEN1 适用: 人, 小鼠 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Multiple Endocrine Neoplasia 1 (MEN1) antibodyKD Validated MEN1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2590 unconjugated Recombinant Antibody
anti-Multiple Endocrine Neoplasia 1 (MEN1) (C-Term) antibodyMEN1 适用: 人, 小鼠 WB, ChIP, ChIP-seq 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))
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别名
- MEN1
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背景
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Background: The MEN1 gene encodes menin, a nuclear scaffold protein that regulates gene transcription by coordinating chromatin remodeling. It is mapped to 11q13.1. MEN1 is considered to act as a tumor suppressor gene. It has been found that that MEN1 inactivation by antisense RNA antagonizes transforming growth factor-beta-mediated cell growth inhibition. Overexpression of MEN1 in an inducible cell culture system downregulated the proximal promoter. In vitro studies have shown that MEN1 is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD. What's more, MEN1 was essential to maintain MLL-associated myeloid transformation.
Gene Full Name: menin 1
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基因ID
- 4221
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UniProt
- O00255
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途径
- Chromatin Binding, Positive Regulation of Endopeptidase Activity
抗原
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