MALT1 抗体 (C-Term)
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北京 101111
Quick Overview for MALT1 抗体 (C-Term) (ABIN8011982)
抗原
See all MALT1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- C-Term
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原理
- Anti-MALT1 Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-MALT1 Antibody. Tested in Flow Cytometry, ICC/IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human MALT1.
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亚型
- IgG
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anti-Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) (AA 125-450) antibody
MALT1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) (AA 1-813) antibodyMALT1 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) (AA 1-813) antibodyMALT1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E12 unconjugated
anti-Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) (AA 701-808) antibodyMALT1 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal MT1-410 unconjugated
anti-Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) antibodyMALT1 适用: 人 WB, FACS, ICC 宿主: 兔 Monoclonal 24GB440 unconjugated Recombinant Antibody
anti-Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) (AA 701-808) antibodyMALT1 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal rMT1-410 unconjugated Recombinant Antibody
anti-Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) (AA 701-808) antibodyMALT1 适用: 人 WB, IHC 宿主: 兔 Monoclonal MT1-3159R unconjugated Recombinant Antibody
anti-Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) (AA 685-784) antibodyMALT1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) (AA 1-813) antibodyMALT1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) antibodyMALT1 适用: 人 WB 宿主: 小鼠 Monoclonal 24GB5835 unconjugated
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应用备注
- Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry(Fixed), 1-3 μg/1x106 cells, Human
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- MALT1 (Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1))
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别名
- MALT1
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背景
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Background: MALT1 (Mucosa-associated lymphoid tissue lymphoma translocation protein 1), also called MLT or PARACASPASE, is a protein that in humans is encoded by the MALT1 gene. This gene has been found to be recurrently rearranged in chromosomal translocation with two other genes - baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) and immunoglobulin heavy chain locus - in mucosa-associated lymphoid tissue lymphomas. Dierlamm et al. (1999) and Akagi et al. (1999) mapped the MALT1 gene to chromosome 18q21. Using mouse models, Ruland et al. (2003) demonstrated that MALT1 is essential for T-cell activation, proliferation, and IL2 production in response to T-cell receptor ligation and strictly required for signal-specific NF-kappa-B (NFKB) activation induced by the T-cell receptor but not TNF-alpha or IL1 signaling. MALT1 operates downstream of BCL10, controls the catalytic activity of the canonical I-kappa-B kinase complex, and regulates the signaling of JNK and p38 MAP kinases.
Gene Full Name: MALT1 paracaspase
Sequence Similarities: Belongs to the peptidase C14B family.
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分子量
- 92 kDa
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基因ID
- 10892
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UniProt
- Q9UDY8
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
抗原
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