MFN2 抗体 (AA 601-757) (PE)
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北京 101111
Quick Overview for MFN2 抗体 (AA 601-757) (PE) (ABIN8010869)
抗原
See all MFN2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 601-757
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原理
- Anti-Mitofusin 2/MFN2 Antibody PE Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- Human Mitofusin 2 shares 96%,95% amino acid (aa) sequence identity with mouse,rat Mitofusin 2,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Mitofusin 2 recombinant protein (Position: V601-R757). Human Mitofusin 2 shares 96% and 95% amino acid (aa) sequence identity with mouse and rat Mitofusin 2, respectively.
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亚型
- IgG
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anti-Mitofusin 2 (MFN2) (AA 661-757) antibody
MFN2 适用: 人 WB, ELISA, IHC (p), RNAi 宿主: 小鼠 Monoclonal 4H8 unconjugated
anti-Mitofusin 2 (MFN2) (AA 1-120) antibodyMFN2 适用: 人, 大鼠, 小鼠, 兔 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 2 (MFN2) (AA 500-600) antibodyMFN2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 2 (MFN2) (AA 447-476) antibodyMFN2 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21136 unconjugated
anti-Mitofusin 2 (MFN2) (AA 687-757) antibodyMFN2 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 2 (MFN2) (AA 601-757) antibodyMFN2 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 2 (MFN2) (AA 370-600) antibody (Atto 390)MFN2 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S153-5 Atto 390
anti-Mitofusin 2 (MFN2) (AA 370-600) antibody (Atto 488)MFN2 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S153-5 Atto 488
anti-Mitofusin 2 (MFN2) (AA 370-600) antibody (FITC)MFN2 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S153-5 FITC
anti-Mitofusin 2 (MFN2) (AA 370-600) antibody (Atto 594)MFN2 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S153-5 Atto 594
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- MFN2 (Mitofusin 2 (MFN2))
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别名
- MFN2
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背景
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Background: Mitofusin-2 is a protein that in humans is encoded by the MFN2 gene. It is mapped to chromosome 1 and encodes a 757-amino acid protein that contains an ATP/GTP-binding site motif. This gene is expressed in many tissues and cell lines such as brain and KG-1 with the highest expression in heart and skeletal muscle. It has been found that MFN2 triggers mitochondrial energization, at least in part, by regulating OXPHOS expression through signals that are independent of its role as a mitochondrial fusion protein. And it contributes to the maintenance and operation of the mitochondrial network. Axonal CMT type 2A and autosomal dominant HMSN VI are caused by MFN2 and mutations in MFN2, which emphasizes its important role of mitochondrial function for both optic atrophies and peripheral neuropathies.
Gene Full Name: mitofusin 2
Sequence Similarities: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. Mitofusin subfamily.
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基因ID
- 9927
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UniProt
- O95140
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途径
- Skeletal Muscle Fiber Development
抗原
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