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MFN2 抗体 (AA 601-757)

Name: MFN2 抗体 (AA 601-757)
SKU: ABIN3042362
Availability: OutOfStock

MFN2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

Anti- Mitofusin-2 Picoband antibody, Western blotting All lanes: Anti Mitofusin-2 at 0. (MFN2 抗体 (AA 601-757))

Western Blotting (WB) image for anti-Mitofusin 2 (MFN2) (AA 601-757) antibody (ABIN3042362) (MFN2 抗体 (AA 601-757))

Western blot analysis of Mitofusin 2 using anti- Mitofusin 2 antibody . (MFN2 抗体 (AA 601-757))

3 images

(1 reference)

产品编号 ABIN3042362

发货至: 中国

Datasheet as PDF

抗原 See all MFN2 抗体

MFN2 (Mitofusin 2 (MFN2))
抗原表位
29

16

7

6

5

3

2

2

2

1

1

1

1

1

1

1

1
AA 601-757
适用
74

52

36

20

4

4

4

4

3

2

2

2

2

1

1

1

1
人
宿主
61

32

2
兔
Compatible Secondaries
克隆类型
62

33
多克隆
标记
34

7

7

6

6

4

3

3

3

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1
This MFN2 antibody is un-conjugated
应用范围
84

46

34

23

22

16

16

13

13

8

3

1

1

1
Western Blotting (WB)

原理

Rabbit IgG polyclonal antibody for Mitofusin-2(MFN2) detection. Tested with WB in Human.

交叉反应（详细）

No cross reactivity with other proteins.

产品特性

Rabbit IgG polyclonal antibody for Mitofusin-2(MFN2) detection. Tested with WB in Human.
Gene Name: mitofusin 2
Protein Name: Mitofusin-2

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human Mitofusin 2 recombinant protein (Position: V601-R757). Human Mitofusin 2 shares 96% and 95% amino acid (aa) sequence identity with mouse and rat Mitofusin 2, respectively.

亚型

IgG

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MFN2 适用: 人 WB, ELISA, IHC (p), RNAi 宿主: 小鼠 Monoclonal 4H8 unconjugated

anti-Mitofusin 2 (MFN2) (AA 1-120) antibody
MFN2 适用: 人, 小鼠, 大鼠, 兔 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Mitofusin 2 (MFN2) (AA 500-600) antibody
MFN2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Mitofusin 2 (MFN2) (AA 687-757) antibody
MFN2 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Mitofusin 2 (MFN2) (AA 447-476) antibody
MFN2 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

anti-Mitofusin 2 (MFN2) (AA 370-600) antibody
MFN2 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S153-5 unconjugated

anti-Mitofusin 2 (MFN2) (AA 370-600) antibody (HRP)
MFN2 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S153-5 HRP

anti-Mitofusin 2 (MFN2) (AA 370-600) antibody (FITC)
MFN2 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S153-5 FITC

anti-Mitofusin 2 (MFN2) (N-Term) antibody
MFN2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Mitofusin 2 (MFN2) (AA 370-600) antibody (Alkaline Phosphatase (AP))
MFN2 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S153-5 Alkaline Phosphatase (AP)

应用备注

WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for Mitofusin 2 is approximately 0.25 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Montaigne, Marechal, Coisne, Debry, Modine, Fayad, Potelle, El Arid, Mouton, Sebti, Duez, Preau, Remy-Jouet, Zerimech, Koussa, Richard, Neviere, Edme, Lefebvre, Staels: "Myocardial contractile dysfunction is associated with impaired mitochondrial function and dynamics in type 2 diabetic but not in obese patients." in: Circulation, Vol. 130, Issue 7, pp. 554-64, (2014) (PubMed).
抗原

MFN2 (Mitofusin 2 (MFN2))

别名

MFN2 (MFN2 产品)

别名

CG3869 antibody, Dmel\\CG3869 antibody, MARF antibody, Marf-1 antibody, Mfn antibody, anon-WO0125274.3 antibody, dMFN antibody, dMfn antibody, dmfn antibody, marf antibody, mfn antibody, mfn2 antibody, MFN2 antibody, hsg antibody, cmt2a antibody, cprp1 antibody, cmt2a2 antibody, CMT2A antibody, CMT2A2 antibody, CPRP1 antibody, HSG antibody, D630023P19Rik antibody, Fzo antibody, mg:cb01g09 antibody, si:dkeyp-104h9.2 antibody, wu:fb79a11 antibody, mitofusin 2 antibody, Mitochondrial assembly regulatory factor antibody, mitofusin-2 antibody, mitofusin 2 L homeolog antibody, MFN2 antibody, Marf antibody, mfn2 antibody, LOC100186475 antibody, Mfn2 antibody, mfn2.L antibody

背景

Mitofusin-2 is a protein that in humans is encoded by the MFN2 gene. It is mapped to chromosome 1 and encodes a 757-amino acid protein that contains an ATP/GTP-binding site motif. This gene is expressed in many tissues and cell lines such as brain and KG-1 with the highest expression in heart and skeletal muscle. It has been found that MFN2 triggers mitochondrial energization, at least in part, by regulating OXPHOS expression through signals that are independent of its role as a mitochondrial fusion protein. And it contributes to the maintenance and operation of the mitochondrial network. Axonal CMT type 2A and autosomal dominant HMSN VI are caused by MFN2 and mutations in MFN2, which emphasizes its important role of mitochondrial function for both optic atrophies and peripheral neuropathies.

Synonyms: CMT2A antibody|CMT2A2 antibody|CPRP 1 antibody|CPRP1 antibody|Fzo antibody|HSG antibody|hyperplasia suppressor gene antibody|Hypertension related protein 1 antibody|KIAA0214 antibody|MARF antibody|MFN 2 antibody|Mfn2 antibody|MFN2_HUMAN antibody|Mitochondrial assembly regulatory factor antibody|Mitofusin-2 antibody|Mitofusin2 antibody|Transmembrane GTPase MFN2 antibody

基因ID

9927

UniProt

O95140

途径

Skeletal Muscle Fiber Development