MFN1 抗体 (N-Term) (Biotin)
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北京 101111
Quick Overview for MFN1 抗体 (N-Term) (Biotin) (ABIN8010839)
抗原
See all MFN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Anti-Mitofusin 1/MFN1 Antibody Biotin Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- different from the related mouse,rat sequences by one amino acid.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminal of human Mitofusin 1, different from the related mouse and rat sequences by one amino acid.
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亚型
- IgG
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anti-Mitofusin 1 (MFN1) (AA 1-741) antibody
MFN1 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 3C9 unconjugated
anti-Mitofusin 1 (MFN1) (AA 1-234) antibodyMFN1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 1 (MFN1) (AA 651-741) antibodyMFN1 适用: 小鼠, 大鼠, 兔, 小鸡 WB, ELISA, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 1 (MFN1) antibodyKD Validated MFN1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB4970 unconjugated Recombinant Antibody
anti-Mitofusin 1 (MFN1) (Internal Region) antibodyMFN1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 1 (MFN1) (AA 622-741) antibodyMFN1 适用: 人 WB, IHC, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 1 (MFN1) (AA 622-741) antibodyMFN1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 1 (MFN1) (AA 209-469) antibodyMFN1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4D11 unconjugated
anti-Mitofusin 1 (MFN1) (AA 622-741) antibodyMFN1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 1 (MFN1) (AA 745-756) antibodyMFN1 适用: 人, 兔, 犬, 马, 猴 IHC, IHC (p) 宿主: 山羊 Polyclonal unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- MFN1 (Mitofusin 1 (MFN1))
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别名
- MFN1
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背景
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Background: Mitofusin-1 is a protein that in humans is encoded by the MFN1 gene. It is an 80-90 kDa mitochondrial member of the dynamin family of molecules. It is ubiquitously expressed, and found in the outer mitochondrial membrane. The protein encoded by this gene is a mediator of mitochondrial fusion, and thereby contribute to the dynamic balance between fusion and fission that determines mitochondria morphology. MFN1 is known to form oligomers, either with itself or MFN-2, and to undergo ubiquitination by MARCH5. MFN-1 has two key domains. One is a coiled-coil region that mediates MFN-1: MFN-1/2 binding, and a second is a GTPase domain whose cleavage of GTP is necessary for membrane fusion. Overexpression of MFN1 caused perinuclear mitochondrial clustering.
Gene Full Name: mitofusin 1
Sequence Similarities: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. Mitofusin subfamily.
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基因ID
- 55669
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UniProt
- Q8IWA4
抗原
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