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MCM7 抗体 (AA 526-719) (HRP)

The 兔 多克隆 anti-MCM7 antibody is suitable to detect MCM7 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IHC 和 ELISA.
产品编号 ABIN8010438
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MCM7 抗体 (AA 526-719) (HRP) (ABIN8010438)

抗原

See all MCM7 抗体
MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))

适用

  • 204
  • 58
  • 50
  • 13
  • 11
  • 10
  • 9
  • 9
  • 4
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 135
  • 67
  • 2

克隆类型

  • 107
  • 97
多克隆

标记

  • 97
  • 12
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
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  • 3
  • 3
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  • 3
  • 3
  • 3
  • 3
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  • 3
  • 2
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This MCM7 antibody is conjugated to HRP

应用范围

  • 143
  • 81
  • 68
  • 62
  • 38
  • 28
  • 21
  • 20
  • 15
  • 13
  • 13
  • 4
  • 2
  • 2
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  • 1
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 50
    • 24
    • 15
    • 15
    • 9
    • 9
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 526-719

    原理

    Anti-MCM7 Antibody HRP Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human MCM7 shares 94% amino acid (aa) sequence identity with mouse MCM7.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human MCM7 recombinant protein (Position: D526-V719). Human MCM7 shares 94% amino acid (aa) sequence identity with mouse MCM7.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))

    别名

    MCM7

    背景

    Background: MCM7 (Minichromosome Maintenance, s. Cerevisiae, homolog of, 7), also called CDC47, FORMERLY, is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The MCM7 gene is mapped to 7q22.1. MCM7 plays a pivotal role in the G1/S phase transition, orchestrating the correct assembly of replication forks on chromosomal DNA and ensuring that all the genome is replicated once and not more than once at each cell cycle. The MCM7 gene contains 15 exons. The miRNAs MIR106B, MIR93, and MIR25 are clustered in a 5-prime to 3-prime orientation within intron 13. It has been found that MCM7 and the precursors of microRNAs (miRNAs) MIR106B, MIR93, and MIR25, all of which arise from intron 13 of the MCM7 gene, were overexpressed with almost perfect correlation in 5 of 10 human gastric tumors.

    Gene Full Name: minichromosome maintenance complex component 7

    Sequence Similarities: Belongs to the MCM family.

    基因ID

    4176

    UniProt

    P33993

    途径

    DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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