GANP 抗体 (AA 1275-1715) (Cy3)
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Quick Overview for GANP 抗体 (AA 1275-1715) (Cy3) (ABIN8010334)
抗原
See all GANP (MCM3AP) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1275-1715
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原理
- Anti-GANP/MCM3AP Antibody Cy3 Conjugated
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交叉反应 (详细)
- No cross reactivity with other proteins.
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预测反应
- Human MCM3AP shares 80.9% amino acid (aa) sequence identity with mouse MCM3AP.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human GANP/MCM3AP recombinant protein (Position: R1275-H1715). Human MCM3AP shares 80.9% amino acid (aa) sequence identity with mouse MCM3AP.
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亚型
- IgG
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应用备注
- Flow Cytometry, 1-3 μg/1x106 cells
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- GANP (MCM3AP) (Minichromosome Maintenance Complex Component 3 Associated Protein (MCM3AP))
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别名
- MCM3AP
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背景
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Background: 80 kDa MCM3-associated protein is a protein that in humans is encoded by the MCM3AP gene. The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization. This gene is expressed in the brain or in neuronal tissue. An allelic variant encoding amino acid Lys at 915, instead of conserved Glu, has been identified in patients with mild intellectual disability.
Gene Full Name: minichromosome maintenance complex component 3 associated protein
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基因ID
- 8888
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UniProt
- O60318
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途径
- Protein targeting to Nucleus
抗原
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