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Midkine 抗体 (AA 21-143) (Fluoro488)

The Fluoro488-conjugated 兔 多克隆 anti-Midkine antibody (ABIN8010181) specifically detects Midkine in FACS. The antibody is reactive with 人 samples.
产品编号 ABIN8010181
发货至: 中国
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Quick Overview for Midkine 抗体 (AA 21-143) (Fluoro488) (ABIN8010181)

抗原

See all Midkine (MDK) 抗体
Midkine (MDK) (Midkine (Neurite Growth-Promoting Factor 2) (MDK))

适用

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宿主

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克隆类型

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多克隆

标记

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This Midkine antibody is conjugated to Fluoro488

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 21-143

    原理

    Anti-Midkine/MDK Antibody Fluoro488 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human Midkine shares 87%,89% amino acid (aa) sequence identity with mouse,rat Midkine,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Midkine recombinant protein (Position: V21-D143). Human Midkine shares 87% and 89% amino acid (aa) sequence identity with mouse and rat Midkine, respectively.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    Midkine (MDK) (Midkine (Neurite Growth-Promoting Factor 2) (MDK))

    别名

    MDK

    背景

    Background: Midkine (MK or MDK), also known as neurite growth-promoting factor 2 (NEGF2), is a protein that in humans is encoded by the MDK gene. Midkine is a basic heparin-binding growth factor of low molecular weight, and forms a family with pleiotrophin (NEGF1, 46% homologous with MK). It is a nonglycosylated protein, composed of two domains held by disulfide bridges. It is a developmentally important retinoic acid-responsive gene product strongly induced during mid-gestation, hence the name midkine. Restricted mainly to certain tissues in the normal adult, it is strongly induced during oncogenesis, inflammation and tissue repair. Midkine is pleiotropic, capable of exerting activities such as cell proliferation, cell migration, angiogenesis and fibrinolysis. A molecular complex containing receptor-type tyrosine phosphatase zeta (PTPζ), low density lipoprotein receptor-related protein (LRP1), anaplastic leukemia kinase (ALK) and syndecans is considered to be its receptor.

    Gene Full Name: midkine

    Sequence Similarities: Contains 3 Ig-like C2-type (immunoglobulin-like) domains.

    基因ID

    4192

    UniProt

    P21741

    途径

    RTK signaling, M Phase, Skeletal Muscle Fiber Development
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