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MBD4 抗体 (AA 238-534) (HRP)

This 兔 多克隆 antibody specifically detects MBD4 in WB, ELISA 和 IHC. It exhibits reactivity toward 小鼠 和 大鼠.
产品编号 ABIN8009612
发货至: 中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MBD4 抗体 (AA 238-534) (HRP) (ABIN8009612)

抗原

See all MBD4 抗体
MBD4 (Methyl-CpG Binding Domain Protein 4 (MBD4))

适用

  • 40
  • 39
  • 38
  • 1
小鼠, 大鼠

宿主

  • 50
  • 1

克隆类型

  • 50
  • 1
多克隆

标记

  • 22
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
This MBD4 antibody is conjugated to HRP

应用范围

  • 30
  • 25
  • 18
  • 10
  • 5
  • 4
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 13
    • 13
    • 12
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 238-534

    原理

    Anti-Mbd4 Antibody HRP Conjugated

    交叉反应 (详细)

    No cross reactivity with other proteins.

    预测反应

    Mouse Mbd4 shares 69.7% amino acid (aa) sequence identity with human MBD4.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived mouse Mbd4 recombinant protein (Position: R238-D534). Mouse Mbd4 shares 69.7% amino acid (aa) sequence identity with human MBD4.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    MBD4 (Methyl-CpG Binding Domain Protein 4 (MBD4))

    别名

    Mbd4

    背景

    Background: Methyl-CpG-binding domain protein 4 is a protein that in humans is encoded by the MBD4 gene. It is mapped to 3q21.3. The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains an MBD domain at the N-terminus that functions both in binding to methylated DNA and in protein interactions and a C-terminal mismatch-specific glycosylase domain that is involved in DNA repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

    Gene Full Name: methyl-CpG binding domain protein 4

    基因ID

    17193

    UniProt

    Q9Z2D7

    途径

    DNA Damage Repair
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