MBD4 抗体 (AA 16-580) (Fluoro594)
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Quick Overview for MBD4 抗体 (AA 16-580) (Fluoro594) (ABIN8009599)
抗原
See all MBD4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 16-580
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原理
- Anti-MBD4/MED1 Antibody Fluoro594 Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MBD4/MED1 recombinant protein (Position: A16-S580).
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- MBD4 (Methyl-CpG Binding Domain Protein 4 (MBD4))
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别名
- MBD4
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背景
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Background: Methyl-CpG-binding domain protein 4 is a protein that in humans is encoded by the MBD4 gene. It is mapped to 3q21.3. The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains an MBD domain at the N-terminus that functions both in binding to methylated DNA and in protein interactions and a C-terminal mismatch-specific glycosylase domain that is involved in DNA repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene Full Name: methyl-CpG binding domain 4, DNA glycosylase
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基因ID
- 8930
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UniProt
- O95243
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途径
- DNA Damage Repair
抗原
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