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MBD1 抗体 (N-Term) (APC)

The APC-conjugated 兔 多克隆 anti-MBD1 antibody (ABIN8009569) specifically detects MBD1 in FACS. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN8009569
发货至: 中国
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Quick Overview for MBD1 抗体 (N-Term) (APC) (ABIN8009569)

抗原

See all MBD1 抗体
MBD1 (Methyl-CpG Binding Domain Protein 1 (MBD1))

适用

  • 80
  • 31
  • 15
  • 5
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 60
  • 21

克隆类型

  • 48
  • 33
多克隆

标记

  • 37
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MBD1 antibody is conjugated to APC

应用范围

  • 52
  • 31
  • 18
  • 17
  • 13
  • 13
  • 12
  • 12
  • 10
  • 10
  • 7
  • 3
  • 1
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 15
    • 12
    • 7
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    原理

    Anti-MBD1 Antibody APC Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human MBD1.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    MBD1 (Methyl-CpG Binding Domain Protein 1 (MBD1))

    别名

    MBD1

    背景

    Background: MBD1 (Methyl-CpG-Binding Domain Protein 1), also known as PCM1 or CXXC3, is a protein that in humans is encoded by the MBD1 gene. Using PCR on a hybrid panel and FISH, Hendrich et al. (1999) mapped the MBD1 gene to chromosome 18q21, 2.1 cM distal to MBD2. Using yeast 2-hybrid analysis, reciprocal immunoprecipitation analysis, and protein pull-down assays, Fujita et al. (2003) showed that MBD1 interacted ly with MCAF. Deletion analysis revealed that the C-terminal transcriptional repressor domain (TRD) of MBD1 interacted with a conserved C-terminal domain of MCAF. < a href=https://www.bosterbio.com/cells/reporter-cell-lines style=color:#ea8d28>Reporter gene assays showed that MCAF increased the repressive function of the isolated TRD of MBD1 against SP1. Chromatin immunoprecipitation analysis revealed that MBD1 linked MCAF to methylated promoters. Uchimura et al. (2006) found that MBD1 was multiply sumoylated in HeLa cells. Sumoylation did not alter the intracellular localization of MBD1 at nuclear foci in C-33A human cervical cancer cells.

    Gene Full Name: methyl-CpG binding domain protein 1

    基因ID

    4152

    UniProt

    Q9UIS9
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