METAP2 抗体 (AA 201-474)
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北京 101111
Quick Overview for METAP2 抗体 (AA 201-474) (ABIN8009506)
抗原
See all METAP2 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 201-474
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原理
- Anti-METAP2 Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-METAP2 Antibody. Tested in ELISA, IHC, WB, applications. This antibody reacts with Human, Monkey, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human METAP2 recombinant protein (Position: E201-R474).
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亚型
- IgG
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应用备注
- Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat, Monkey Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- METAP2 (Methionyl Aminopeptidase 2 (METAP2))
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别名
- METAP2
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背景
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Background: Methionine aminopeptidase 2 is an enzyme that in humans is encoded by the METAP2 gene. The protein encoded by this gene is a member of the methionyl aminopeptidase family. The encoded protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent proteins. Increased expression of this gene is associated with various forms of cancer, and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. Inhibitors of this gene have also been shown to be effective for the treatment of obesity. A pseudogene of this gene is located on chromosome 2. Several transcript variants encoding different isoforms have been found for this gene.
Gene Full Name: methionyl aminopeptidase 2
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分子量
- 67 kDa
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基因ID
- 10988
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UniProt
- P50579
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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