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TIMP2 抗体 (C-Term) (Fluoro594)

This 兔 多克隆 antibody specifically detects TIMP2 in FACS. It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN8009357
发货至: 中国
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Quick Overview for TIMP2 抗体 (C-Term) (Fluoro594) (ABIN8009357)

抗原

See all TIMP2 抗体
TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This TIMP2 antibody is conjugated to Fluoro594

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    C-Term

    原理

    Anti-Metalloproteinase inhibitor 2 TIMP2 Antibody Fluoro594 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    identical to the related mouse,rat sequences.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human TIMP2, identical to the related mouse and rat sequences.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

    别名

    TIMP2

    背景

    Background: TIMP metallopeptidase inhibitor 2, a tissue inhibitor of metalloproteinases, also known as TIMP2, is a human gene, thought to be a metastasis suppressor. This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to ly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.

    Gene Full Name: TIMP metallopeptidase inhibitor 2

    Sequence Similarities: Belongs to the protease inhibitor I35 (TIMP) family.

    基因ID

    7077

    UniProt

    P16035

    途径

    cAMP Metabolic Process
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