MTDH 抗体 (AA 101-270) (HRP)
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北京 101111
Quick Overview for MTDH 抗体 (AA 101-270) (HRP) (ABIN8009315)
抗原
See all MTDH 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 101-270
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原理
- Anti-LYRIC Antibody (monoclonal, 2E5G3) HRP Conjugated
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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预测反应
- Human LYRIC shares 94% amino acid (aa) sequence identity with both mouse,rat LYRIC.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human LYRIC recombinant protein (Position: D101-Q270). Human LYRIC shares 94% amino acid (aa) sequence identity with both mouse and rat LYRIC.
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亚型
- IgG2b
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anti-Metadherin (MTDH) antibody
MTDH 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Metadherin (MTDH) (AA 101-270) antibodyMTDH 适用: 人, 小鼠, 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Metadherin (MTDH) antibodyMTDH 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Metadherin (MTDH) (AA 1-582) antibodyMTDH 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Metadherin (MTDH) (AA 1-582) antibodyMTDH 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Metadherin (MTDH) antibodyMTDH 适用: 人 WB, IHC, FACS, ELISA 宿主: 小鼠 Monoclonal 2F11C3 unconjugated
anti-Metadherin (MTDH) (AA 1-260) antibodyMTDH 适用: 人 IHC, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-Metadherin (MTDH) antibodyMTDH 适用: 人 WB, FACS, ICC 宿主: 兔 Monoclonal 24GB455 unconjugated Recombinant Antibody
anti-Metadherin (MTDH) (AA 131-230) antibodyMTDH 适用: 人 WB, FACS, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Metadherin (MTDH) antibodyMTDH 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 25GB5810 unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- MTDH (Metadherin (MTDH))
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别名
- MTDH
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背景
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Background: MTDH (Metadherin), also known as protein LYRIC or astrocyte elevated gene-1 protein (AEG-1) is a protein that in humans is encoded by the MTDH gene. AEG-1 is involved in HIF-1alpha mediated angiogenesis. AEG-1 also interacts with SND1 and involved in RNA-induced silencing complex (RISC) and plays very important role in RISC and miRNA functions. AEG-1 induces an oncogene called Late SV40 factor (LSF/TFCP2) which is involved in thymidylate synthase (TS) induction and DNA biosynthesis synthesis. Late SV40 factor (LSF/TFCP2) enhances angiogenesis by transcriptionally up-regulating matrix metalloproteinase-9 (MMP9). AEG-1 acts as an oncogene in melanoma, malignant glioma, breast cancer and hepatocellular carcinoma. It is highly expressed in these cancers and helps in progression and development of these cancers. It is induced by c-Myc oncogene and plays very important role in anchorage independent growth of cancer cells.
Gene Full Name: metadherin
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基因ID
- 92140
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UniProt
- Q86UE4
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途径
- Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization
抗原
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