MME 抗体 (AA 52-750) (Fluoro488)
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Quick Overview for MME 抗体 (AA 52-750) (Fluoro488) (ABIN8008992)
抗原
See all MME 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 52-750
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原理
- Anti-CD10/MME Antibody Fluoro488 Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- Human CD10 shares 94% amino acid (aa) sequences identity with both mouse,rat CD10.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CD10 recombinant protein (Position: Y52-W750). Human CD10 shares 94% amino acid (aa) sequences identity with both mouse and rat CD10.
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亚型
- IgG
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anti-Membrane Metallo-Endopeptidase (MME) (AA 52-246) antibody
MME 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 7D4B1 unconjugated
anti-Membrane Metallo-Endopeptidase (MME) (AA 52-352) antibodyMME 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Membrane Metallo-Endopeptidase (MME) (AA 501-600) antibodyMME 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Membrane Metallo-Endopeptidase (MME) (AA 297-483) antibodyMME 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal MME-1870 unconjugated
anti-Membrane Metallo-Endopeptidase (MME) antibody (PE)MME 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-78 PE
anti-Membrane Metallo-Endopeptidase (MME) (AA 382-538) antibodyMME 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Membrane Metallo-Endopeptidase (MME) (AA 297-483) antibodyMME 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal MME-1892 unconjugated
anti-Membrane Metallo-Endopeptidase (MME) (AA 549-750) antibodyMME 适用: 人 IHC, FACS, ELISA 宿主: 小鼠 Monoclonal 3G6B11 unconjugated
anti-Membrane Metallo-Endopeptidase (MME) (AA 549-750) antibodyMME 适用: 人 WB, FACS, ELISA 宿主: 小鼠 Monoclonal 6G12E12 unconjugated
anti-Membrane Metallo-Endopeptidase (MME) antibody (FITC)MME 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-78 FITC
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- MME (Membrane Metallo-Endopeptidase (MME))
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别名
- MME
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背景
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Background: CD10, also known as membrane metallo-endopeptidase, neutral endopeptidase (NEP), Neprilysin, or common acute lymphoblastic leukemia antigen (CALLA), is a zinc-dependent metalloprotease enzyme that degrades a number of small secreted peptides, most notably theamyloid beta peptide whose abnormal misfolding and aggregation in neural tissue has been implicated as a cause of Alzheimer's disease. This gene is localized to human chromosome 3 by study of somatic cell hybrids and regionalized the location to 3q21-q27 by in situ hybridization. By cDNA transfection analysis, CD10 is confirmed as a functional neutral endopeptidase of the type that has previously been called enkephalinase. CD10 has also been called atriopeptidase. Atriopeptidase specifically degrades atrial natriuretic factor. A specific enzyme inhibitor was developed and reported that it had effects similar to those of low-dose ANF infusion. These effects include diuresis, natriuresis, vasodilatation, and suppression of the renin-angiotensin-aldosterone system.
Gene Full Name: membrane metalloendopeptidase
Sequence Similarities: Belongs to the peptidase M13 family.
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基因ID
- 4311
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UniProt
- P08473
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途径
- RTK signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
抗原
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