MMP2 抗体 (AA 429-660) (FITC)
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Quick Overview for MMP2 抗体 (AA 429-660) (FITC) (ABIN8008302)
抗原
See all MMP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 429-660
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原理
- Anti-MMP2 Antibody FITC Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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预测反应
- coli-derived human MMP2 recombinant protein (Position: K429-C660). Human MMP2 shares 95.7%,95.3% amino acid (aa) sequence identity with mouse,rat MMP2,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human MMP2 recombinant protein (Position: K429-C660). Human MMP2 shares 95.7% and 95.3% amino acid (aa) sequence identity with mouse and rat MMP2, respectively.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- MMP2 (Matrix Metalloproteinase 2 (MMP2))
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别名
- MMP2
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背景
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Background: Matrix metalloproteinase-2 (MMP2) is a Type IV collagenase, 72-kD, which is also known as gelatinase and is a member of a group of secreted zinc metalloproteases. The MMP2 gene is 17 kb long with 13 exons varying in size from 110 to 901 bp and 12 introns ranging from 175 to 4,350 bp, located within a region of human chromosome 16q13. In addition, the extra exons encode the amino acids of the fibronectin-like domain which has so far been found in only the 72- and 92- kDa type IV collagenase. MMP2, which has a critical role in the binding of progelatinase A and TIMP4 via the C-terminal hemopexin-like domain (C domain), is functionally associated on the surface of angiogenic blood vessels. Not only is a likely effector of endometrial menstrual breakdown, MMP2 is also effector and regulator of the inflammatory response. Moreover, MMP2 could be helpful in diagnosing Takayasu arteritis.
Gene Full Name: matrix metallopeptidase 2
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基因ID
- 4313
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UniProt
- P08253
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途径
- Activation of Innate immune Response
抗原
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