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MMP2 抗体 (AA 40-280)

Name: MMP2 抗体 (AA 40-280)
Brand: antibodies-online
SKU: ABIN6143911
Availability: OutOfStock

MMP2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

Western blot analysis of extracts of various cell lines, using MMP2 antibody.

Immunofluorescence analysis of PC-12 cells using MMP2 antibody (ABIN6129301, ABIN6143911, ABIN6143913 and ABIN6221846) at dilution of 1:100.

Immunohistochemistry of paraffin-embedded mouse spleen using MMP2 antibody.

IHC (p)

Immunohistochemistry of paraffin-embedded human stomach using MMP2 antibody.

IHC (p)

Immunofluorescence analysis of U2OS cells using MMP2 antibody.

XIAOPI formula inhibits the proliferation and invasion of 4T1 cells co-cultured with TAMs and HSPCs.

CCL5 promotes the invasion and the PCSCs subpopulation of prostate cancer cells in vitro.

7 images

(6 references)

产品编号 ABIN6143911

发货至: 中国

Datasheet as PDF

抗原 See all MMP2 抗体

MMP2 (Matrix Metalloproteinase 2 (MMP2))
抗原表位
16

16

16

11

10

8

6

6

6

6

5

4

4

4

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
AA 40-280
适用
150

80

65

49

7

5

5

4

2

2

2

1

1
人
宿主
123

42

1
兔
Compatible Secondaries
克隆类型
121

45
多克隆
标记
79

14

13

12

5

3

3

3

3

3

3

3

3

3

3

3

2

1

1

1

1

1

1

1

1
This MMP2 antibody is un-conjugated
应用范围
134

59

52

39

39

36

31

28

18

15

14

4

3

3

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

序列

DVAPKTDKEL AVQYLNTFYG CPKESCNLFV LKDTLKKMQK FFGLPQTGDL DQNTIETMRK PRCGNPDVAN YNFFPRKPKW DKNQITYRII GYTPDLDPET VDDAFARAFQ VWSDVTPLRF SRIHDGEADI MINFGRWEHG DGYPFDGKDG LLAHAFAPGT GVGGDSHFDD DELWTLGEGQ VVRVKYGNAD GEYCKFPFLF NGKEYNSCTD TGRSDGFLWC STTYNFEKDG KYGFCPHEAL F

交叉反应

人, 小鼠, 大鼠

产品特性

Polyclonal Antibodies

免疫原

Recombinant fusion protein containing a sequence corresponding to amino acids 40-280 of human MMP2 (NP_004521.1).

亚型

IgG

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anti-Matrix Metalloproteinase 2 (MMP2) (AA 31-109) antibody
MMP2 适用: 人, 大鼠, 小鼠, 兔 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Matrix Metalloproteinase 2 (MMP2) antibody
MMP2 适用: 人 WB, IP, IF, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Matrix Metalloproteinase 2 (MMP2) (AA 401-500) antibody
MMP2 适用: 人, 大鼠, 小鼠, 兔 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Matrix Metalloproteinase 2 (MMP2) (AA 580-660) antibody
MMP2 适用: 人, 大鼠, 小鼠, 猴 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Matrix Metalloproteinase 2 (MMP2) (C-Term) antibody
MMP2 适用: 人, 大鼠, 小鼠, 兔, Cow, 犬, 豚鼠, 马, 绵羊 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Matrix Metalloproteinase 2 (MMP2) (AA 110-660) antibody
MMP2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Matrix Metalloproteinase 2 (MMP2) (AA 9-140) antibody
MMP2 适用: 人, 小鼠 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 2B11E6 unconjugated

anti-Matrix Metalloproteinase 2 (MMP2) (AA 110-660) antibody
MMP2 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated

anti-Matrix Metalloproteinase 2 (MMP2) antibody
MMP2 适用: 人, 大鼠, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated

anti-Matrix Metalloproteinase 2 (MMP2) (AA 242-396) antibody
MMP2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4D1E2 unconjugated

应用备注

WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

说明

HIGH QUALITY

限制

仅限研究用
状态

Liquid

缓冲液

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C. Avoid freeze / thaw cycles.
Fu, Wang, Wu, Feng, Wang, Zhou, Ma, Wang: "HMGA1 exacerbates tumor growth through regulating the cell cycle and accelerates migration/invasion via targeting miR-221/222 in cervical cancer." in: Cell death & disease, Vol. 9, Issue 6, pp. 594, (2018) (PubMed).

Huang, Song, Sun, Zhang, Huang: "IRX5 promotes NF-κB signalling to increase proliferation, migration and invasion via OPN in tongue squamous cell carcinoma." in: Journal of cellular and molecular medicine, (2018) (PubMed).

Xing, Yu, Zhang, Luo, Lei, Huang, Lin, Huang, Huang, Nong, Zhou, Wei et al.: "Isoviolanthin Extracted from Dendrobium officinale Reverses TGF-β1-Mediated Epithelial⁻Mesenchymal Transition in Hepatocellular Carcinoma Cells via Deactivating the TGF-β/Smad and PI3K/Akt/mTOR ..." in: International journal of molecular sciences, Vol. 19, Issue 6, (2018) (PubMed).

"Retracted: 'Anti-fibrotic actions of Ghrelin by inhibition of the NADPH oxidase-ROS signaling pathway' by Qian Wang, Xin Sui, Rui Chen, Peiyong Ma, Tao Ding, Dianjun Sui, and Ping Yang." in: Clinical and experimental pharmacology & physiology, Vol. 45, Issue 8, pp. 885, (2018) (PubMed).

Wang, Dong, Liu, Xu, Hu, Fan, Chen: "Early growth response factor-1 DNA enzyme 1 inhibits the formation of abdominal aortic aneurysm in rats." in: Experimental and therapeutic medicine, Vol. 16, Issue 1, pp. 141-148, (2018) (PubMed).

Lee, Lee, Bu: "Protective Effects of Dihydrocaffeic Acid, a Coffee Component Metabolite, on a Focal Cerebral Ischemia Rat Model." in: Molecules (Basel, Switzerland), Vol. 20, Issue 7, pp. 11930-40, (2016) (PubMed).
抗原

MMP2 (Matrix Metalloproteinase 2 (MMP2))

别名

MMP2 (MMP2 产品)

别名

2-MMP antibody, CG1794 antibody, DM2-MMP antibody, Dm2-MMP antibody, Dmel\\CG1794 antibody, MMP2 antibody, anon-WO0118547.84 antibody, dm-2MMP antibody, dmmp2 antibody, l(2)02353 antibody, mmp2 antibody, wu:fa99h12 antibody, wu:fk89d01 antibody, fgmmp-2 antibody, Mmp-2 antibody, LOC100135793 antibody, Clg4a antibody, GelA antibody, MMP-2 antibody, CLG4 antibody, CLG4A antibody, MMP-II antibody, MONA antibody, TBE-1 antibody, matrix metallopeptidase 2 antibody, Matrix metalloproteinase 2 antibody, matrix metalloproteinase 2 antibody, matrix metalloproteinase-2 antibody, MMP2 antibody, Mmp2 antibody, mmp2 antibody, LOC657982 antibody, LOC100135793 antibody

背景

This gene is a member of the matrix metalloproteinase (MMP) gene family, that are zinc-dependent enzymes capable of cleaving components of the extracellular matrix and molecules involved in signal transduction. The protein encoded by this gene is a gelatinase A, type IV collagenase, that contains three fibronectin type II repeats in its catalytic site that allow binding of denatured type IV and V collagen and elastin. Unlike most MMP family members, activation of this protein can occur on the cell membrane. This enzyme can be activated extracellularly by proteases, or, intracellulary by its S-glutathiolation with no requirement for proteolytical removal of the pro-domain. This protein is thought to be involved in multiple pathways including roles in the nervous system, endometrial menstrual breakdown, regulation of vascularization, and metastasis. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.,CLG4,CLG4A,MMP-2,MMP-II,MONA,TBE-1,MMP2,Cancer,Tumor biomarkers,Invasion and Metastasis,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Cell Biology & Developmental Biology,Extracellular Matrix,MMPs,Ubiquitin,Endocrine & Metabolism,Cardiovascular,Angiogenesis,Hypoxia,MMP2

分子量

65 kDa/68 kDa/73 kDa

基因ID

4313

UniProt

P08253

途径

Activation of Innate immune Response