MMP7 抗体 (AA 95-264) (Fluoro550)
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Quick Overview for MMP7 抗体 (AA 95-264) (Fluoro550) (ABIN8008223)
抗原
See all MMP7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 95-264
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原理
- Anti-MMP7 Antibody Fluoro550 Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Mouse MMP7 shares 71%,90% amino acid (aa) sequences identity with human,rat MMP7,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived mouse MMP7 recombinant protein (Position: Y95-L264). Mouse MMP7 shares 71% and 90% amino acid (aa) sequences identity with human and rat MMP7, respectively.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- MMP7 (Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7))
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别名
- MMP7
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背景
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Background: Matrix metalloproteinase-7 (MMP-7) previously called putative metalloproteinase I (PUMP1) or matrilysin. The MMP-7 gene has been identified through studies of collagenase-related connective-tissue-degrading metalloproteinases produced by human tumors. The MMP-7 protein has 267 amino acids and is significantly shorter than stromelysin or collagenase (477 and 469 amino acids, respectively). Matrix metalloproteinases play a crucial role in tumor invasion and metastasis. MMP-7, a member of the matrix metalloproteinase family, is structurally different from the other matrix metalloproteinases by virtue of the absence of a conserved COOH-terminal protein domain. In addition, MMP-7 mRNA is regulated in a specific and distinct manner in normal and malignant tissues. MMP-7 has been shown to correlate with nodal or distant metastasis in colorectal carcinomas, however, its implication in early invasive colorectal carcinomas has not been determined. MMP-7 is also a mediator of pulmonary fibrosis and a potential therapeutic target. The standard product used in this kit is recombinant human MMP-7, consisting of 250 amino acids with the molecular mass of 28KDa. The detected MMP-7 includes zymogen and active enzyme.
Gene Full Name: matrix metallopeptidase 7
Sequence Similarities: Belongs to the peptidase M10A family.
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基因ID
- 17393
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UniProt
- Q10738
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途径
- Production of Molecular Mediator of Immune Response
抗原
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