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MMP12 抗体 (AA 237-442) (PE)

The PE-conjugated 兔 多克隆 anti-MMP12 antibody (ABIN8008063) specifically detects MMP12 in FACS. The antibody is reactive with 小鼠 samples.
产品编号 ABIN8008063
发货至: 中国
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Quick Overview for MMP12 抗体 (AA 237-442) (PE) (ABIN8008063)

抗原

See all MMP12 抗体
MMP12 (Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12))

适用

  • 89
  • 61
  • 38
  • 6
  • 1
小鼠

宿主

  • 132
  • 3
  • 3
  • 2
  • 1

克隆类型

  • 123
  • 18
多克隆

标记

  • 54
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  • 3
  • 3
  • 3
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  • 2
  • 2
  • 1
  • 1
  • 1
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This MMP12 antibody is conjugated to PE

应用范围

  • 99
  • 42
  • 37
  • 26
  • 16
  • 12
  • 12
  • 9
  • 5
  • 1
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 29
    • 12
    • 9
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
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    AA 237-442

    原理

    Anti-Mmp12 Antibody PE Conjugated

    交叉反应 (详细)

    No cross reactivity with other proteins.

    预测反应

    Mouse Mmp12 shares 62.7%,90.3% amino acid (aa) sequence identity with mouse,rat Mmp12,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived mouse Mmp12 recombinant protein (Position: K237-H442). Mouse Mmp12 shares 62.7% and 90.3% amino acid (aa) sequence identity with mouse and rat Mmp12, respectively.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    MMP12 (Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12))

    别名

    Mmp12

    背景

    Background: Matrix metalloproteinase-12 (MMP-12) also known as macrophage metalloelastase (MME) or macrophage elastase (ME) is an enzyme that in humans is encoded by the MMP12 gene. This gene encodes a member of the matrix metalloproteinase family of extracellular matrix-degrading enzymes that are involved in tissue remodeling, wound repair, progression of atherosclerosis and tumor invasion. The encoded preproprotein undergoes proteolytic processing to generate a mature, zinc-dependent endopeptidase enzyme. Mice lacking the encoded protein have a diminished capacity to degrade extracellular matrix components, do not develop emphysema in response to long-term exposure to cigarette smoke, and exhibit impaired clearance and increased mortality upon bacterial infection. This gene is located in a cluster of other matrix metalloproteinase genes on chromosome 9. Alternate splicing generates multiple transcript variants encoding distinct isoforms.

    Gene Full Name: matrix metallopeptidase 12

    基因ID

    17381

    UniProt

    P34960
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