Kdm6b 抗体 (AA 1127-1643) (Biotin)
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北京 101111
Quick Overview for Kdm6b 抗体 (AA 1127-1643) (Biotin) (ABIN8006988)
抗原
See all Kdm6b 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1127-1643
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原理
- Anti-KDM6B/JMJD3 Antibody Biotin Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human KDM6B/JMJD3 recombinant protein (Position: R1127-R1643).
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亚型
- IgG
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anti-Lysine (K)-Specific Demethylase 6B (Kdm6b) (AA 1-30), (N-Term) antibody
Kdm6b 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB10077 unconjugated
anti-Lysine (K)-Specific Demethylase 6B (Kdm6b) (AA 265-450) antibodyKdm6b 适用: 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 6B (Kdm6b) (AA 1606-1641), (C-Term) antibodyKdm6b 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB10081-RB10082 unconjugated
anti-Lysine (K)-Specific Demethylase 6B (Kdm6b) (AA 1-30) antibodyKdm6b 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 6B (Kdm6b) (AA 954-987) antibodyKdm6b 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB10080 unconjugated
anti-Lysine (K)-Specific Demethylase 6B (Kdm6b) (AA 1127-1643) antibodyKdm6b 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 6B (Kdm6b) (AA 1023-1057) antibodyKdm6b 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB50943 unconjugated
anti-Lysine (K)-Specific Demethylase 6B (Kdm6b) (AA 879-912) antibodyKdm6b 适用: 小鼠 WB 宿主: 兔 Polyclonal RB51280 unconjugated
anti-Lysine (K)-Specific Demethylase 6B (Kdm6b) (AA 1613-1662) antibodyKdm6b 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 6B (Kdm6b) (AA 1530-1682) antibodyKdm6b 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- Kdm6b (Lysine (K)-Specific Demethylase 6B (Kdm6b))
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别名
- KDM6B
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背景
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Background: Lysine demethylase 6B is a protein that in humans is encoded by the KDM6B gene. It is mapped to 17p13.1. The protein encoded by this gene is a lysine-specific demethylase that specifically demethylates di- or tri-methylated lysine 27 of histone H3 (H3K27me2 or H3K27me3). H3K27 trimethylation is a repressive epigenetic mark controlling chromatin organization and gene silencing. This protein can also demethylate non-histone proteins such as retinoblastoma protein. Through its demethylation actvity this gene influences cellular differentiation and development, tumorigenesis, inflammatory diseases, and neurodegenerative diseases. This protein has two classical nuclear localization signals at its N-terminus. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Gene Full Name: lysine demethylase 6B
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基因ID
- 23135
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UniProt
- O15054
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途径
- Warburg Effect
抗原
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