LAT 抗体 (AA 29-217)
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北京 101111
Quick Overview for LAT 抗体 (AA 29-217) (ABIN8006250)
抗原
See all LAT 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 29-217
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原理
- Anti-Lat Antibody
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交叉反应 （详细）
- No cross reactivity with other proteins.
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预测反应
- Mouse Lat shares 68.4%,93.1% amino acid (aa) sequence identity with human,rat Lat,respectively.
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产品特性
- Anti-Lat Antibody. Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived mouse Lat recombinant protein (Position: R29-E217). Mouse Lat shares 68.4% and 93.1% amino acid (aa) sequence identity with human and rat Lat, respectively.
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亚型
- IgG
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anti-Linker For Activation of T Cells (LAT) (Cytoplasmic Domain) antibody
LAT 适用: 人 WB, IP, ICFC 宿主: 小鼠 Monoclonal LAT-01 unconjugated
anti-Linker For Activation of T Cells (LAT) antibodyLAT 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Linker For Activation of T Cells (LAT) (pTyr191) antibodyLAT 适用: 人 WB, ELISA, IHC, IP, IF 宿主: 兔 Monoclonal 2E4 unconjugated Recombinant Antibody
anti-Linker For Activation of T Cells (LAT) antibodyKD Validated LAT 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB4940 unconjugated Recombinant Antibody
anti-Linker For Activation of T Cells (LAT) (AA 1-233) antibodyLAT 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3B11-1D5 unconjugated
anti-Linker For Activation of T Cells (LAT) (pTyr161) antibodyLAT 适用: 人 ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Linker For Activation of T Cells (LAT) (Cytoplasmic Domain) antibodyLAT 适用: 人 WB, IHC, IP, IHC (p) 宿主: 小鼠 Monoclonal LAT1111 unconjugated
anti-Linker For Activation of T Cells (LAT) (pTyr200) antibodyLAT 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Linker For Activation of T Cells (LAT) (AA 30-237) antibodyLAT 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Linker For Activation of T Cells (LAT) (AA 1-233) antibodyLAT 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Western blot, 0.1-0.25 μg/mL, Mouse Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Mouse ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- LAT (Linker For Activation of T Cells (LAT))
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别名
- Lat
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背景
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Background: The Linker for activation of T cells, also known as linker of activated T cells or LAT, is a protein involved in the T-cell antigen receptor signal transduction pathway which in humans is encoded by the LAT gene. The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene Full Name: linker for activation of T cells
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分子量
- 38 kDa
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基因ID
- 16797
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UniProt
- O54957
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway
抗原
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