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LAT 抗体 (pTyr200)

The 兔多克隆 anti-LAT antibody (ABIN6256669) specifically detects LAT in WB 和 IHC. The antibody is reactive with 人和小鼠 samples.

ABIN6267133 at 1/100 staining Human thyroid cancer tissue by IHC-P. (LAT 抗体 (pTyr200))

IHC

2 images

产品编号 ABIN6256669

发货至: 中国

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中国
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Quick Overview for LAT 抗体 (pTyr200) (ABIN6256669)

抗原

See all LAT 抗体

LAT (Linker For Activation of T Cells (LAT))

适用

人, 小鼠

宿主

兔

克隆类型

多克隆

标记

This LAT antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product LAT Primary Antibody

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pTyr200

特异性

Phospho-LAT (Tyr200) Antibody detects endogenous levels of LAT.

交叉反应

人, 小鼠

纯化方法

The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

免疫原

A synthesized peptide derived from human LAT around the phosphorylation site of Tyr200.

亚型

IgG
anti-Linker For Activation of T Cells (LAT) (Cytoplasmic Domain) antibody
LAT 适用: 人 WB, IP, ICFC 宿主: 小鼠 Monoclonal LAT-01 unconjugated

anti-Linker For Activation of T Cells (LAT) antibody
LAT 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Linker For Activation of T Cells (LAT) (pTyr191) antibody
LAT 适用: 人 WB, ELISA, IHC, IP, IF 宿主: 兔 Monoclonal 2E4 unconjugated Recombinant Antibody

anti-Linker For Activation of T Cells (LAT) antibody
KD Validated LAT 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB4940 unconjugated Recombinant Antibody

anti-Linker For Activation of T Cells (LAT) (AA 1-233) antibody
LAT 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3B11-1D5 unconjugated

anti-Linker For Activation of T Cells (LAT) (pTyr161) antibody
LAT 适用: 人 ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Linker For Activation of T Cells (LAT) (AA 30-237) antibody
LAT 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Linker For Activation of T Cells (LAT) (Cytoplasmic Domain) antibody
LAT 适用: 人 WB, IHC, IP, IHC (p) 宿主: 小鼠 Monoclonal LAT1111 unconjugated

anti-Linker For Activation of T Cells (LAT) (AA 25-221) antibody
LAT 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Linker For Activation of T Cells (LAT) (AA 33-227) antibody
LAT 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:500-1:2000, IHC 1:50-1:200

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20 °C.Stable for 12 months from date of receipt

有效期

12 months
抗原

LAT (Linker For Activation of T Cells (LAT))

别名

LAT

背景

Description: Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.
Gene: LAT

分子量

36, 38kDa

基因ID

27040

UniProt

O43561

途径

TCR Signaling, Fc-epsilon Receptor Signaling Pathway