LIN7C 抗体 (AA 1-73)
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北京 101111
Quick Overview for LIN7C 抗体 (AA 1-73) (ABIN8006195)
抗原
See all LIN7C 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 1-73
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原理
- Anti-LIN7C Antibody
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交叉反应 （详细）
- No cross reactivity with other proteins.
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产品特性
- Anti-LIN7C Antibody. Tested in ELISA, IHC, WB, Flow Cytometry applications. This antibody reacts with Human, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human LIN7C recombinant protein (Position: M1-A73).
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亚型
- IgG
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anti-Lin-7 Homolog C (LIN7C) (N-Term) antibody
LIN7C 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔, Bat, 小鸡, Hamster, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lin-7 Homolog C (LIN7C) (AA 168-197), (C-Term) antibodyLIN7C 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB32322 unconjugated
anti-Lin-7 Homolog C (LIN7C) (AA 108-157) antibodyLIN7C 适用: 人, 大鼠, 小鼠, 斑马鱼, Cow, 犬, 豚鼠, 马, 兔, Bat, 小鸡, Hamster, 猴, Pig, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lin-7 Homolog C (LIN7C) (AA 1-70) antibodyLIN7C 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Lin-7 Homolog C (LIN7C) (N-Term) antibodyLIN7C 适用: 人, 大鼠, 小鼠, 斑马鱼, Cow, 犬, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Rat Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- LIN7C (Lin-7 Homolog C (LIN7C))
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别名
- LIN7C
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背景
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Background: Lin-7 homolog C is a protein that in humans is encoded by the LIN7C gene. LIN7C plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. It forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. LIN7C ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. It is also required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.
Gene Full Name: lin-7 cell polarity scaffold C
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分子量
- 22 kDa
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基因ID
- 55327
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UniProt
- Q9NUP9
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途径
- Synaptic Membrane
抗原
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