LIN7C 抗体 (N-Term)
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- 抗原 See all LIN7C 抗体
- LIN7C (Lin-7 Homolog C (LIN7C))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LIN7C antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- MAALGEPVRL ERDICRAIEL LEKLQRSGEV PPQKLQALQR VLQSEFCNAV
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
- 产品特性
- This is a rabbit polyclonal antibody against LIN7C. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human LIN7C
- Top Product
- Discover our top product LIN7C Primary Antibody
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anti-Lin-7 Homolog C (LIN7C) (N-Term) antibody
LIN7C 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Bat, 小鸡, Hamster, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lin-7 Homolog C (LIN7C) (AA 108-157) antibodyLIN7C 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, Bat, 小鸡, Hamster, 猴, Pig, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lin-7 Homolog C (LIN7C) (AA 1-70) antibodyLIN7C 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Lin-7 Homolog C (LIN7C) (AA 168-197), (C-Term) antibodyLIN7C 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB32322 unconjugated
anti-Lin-7 Homolog C (LIN7C) (AA 175-197), (C-Term) antibodyLIN7C 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 197 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- LIN7C (Lin-7 Homolog C (LIN7C))
- 别名
- LIN7C (LIN7C 产品)
- 别名
- LIN7C antibody, fb75b09 antibody, wu:fb75b09 antibody, zgc:101881 antibody, LIN-7-C antibody, LIN-7C antibody, MALS-3 antibody, MALS3 antibody, VELI3 antibody, 9130007B12Rik antibody, AI303698 antibody, AU019331 antibody, AW125731 antibody, D2Ertd520e antibody, Veli3 antibody, lin-7 homolog C, crumbs cell polarity complex component antibody, lin-7 homolog C L homeolog antibody, lin-7 homolog C (C. elegans) antibody, LIN7C antibody, lin7c.L antibody, lin7c antibody, Lin7c antibody
- 背景
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LIN7C plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. It forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. LIN7C ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. It is also required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.
Alias Symbols: FLJ11215, LIN-7-C, LIN-7C, MALS-3, VELI3, MALS3
Protein Interaction Partner: UBC, AMOTL2, LATS2, YAP1, Wwtr1, CFTR, ELAVL1, AMOT, UIMC1, SPATA2, KCNJ12, BAIAP2, ABCA1, HTR2C, CASK, KCNJ4, DLG1, APBA1,
Protein Size: 197 - 分子量
- 22 kDa
- 基因ID
- 55327
- NCBI登录号
- NM_018362, NP_060832
- UniProt
- Q9NUP9
- 途径
- Synaptic Membrane
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