LRRC1 抗体 (AA 120-497) (Biotin)
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北京 101111
Quick Overview for LRRC1 抗体 (AA 120-497) (Biotin) (ABIN8005456)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 120-497
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原理
- Anti-LRRC1 Antibody Biotin Conjugated
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预测反应
- Human LRRC1 shares 91.8% amino acid (aa) sequence identity with mouse LRRC1.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human LRRC1 recombinant protein (Position: L120-R497). Human LRRC1 shares 91.8% amino acid (aa) sequence identity with mouse LRRC1.
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亚型
- IgG
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- LRRC1 (Leucine Rich Repeat Containing 1 (LRRC1))
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别名
- LRRC1
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背景
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Background: Lano is a member of the LAP (leucine-rich repeats and PDZ) family of proteins that also includes Densin-180, Erbin, and hScribble. The LAP proteins generally contain multiple leucine-rich repeat (LRR) domains which serve to target them to the basolateral membrane of epithelial cells. Lano is unique in that it alone does not possess one or more PDZ (PSD95/DLG/ZO-1) domains as do the other members of the LAP family. However, it can bind to the PDZ domain of Erbin in addition to those of membrane-associated and guanylate kinase (MAGUK) proteins which regulate adhesion and plasticity at cell junctions. It has been suggested that it is through these interaction that these LAP proteins participate in the maintenance of proper embryonic development and integrity of epithelial tissues.
Gene Full Name: leucine rich repeat containing 1
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基因ID
- 55227
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UniProt
- Q9BTT6
抗原
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