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LRRC1 抗体 (C-Term)

LRRC1 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500136
发货至: 中国
  • 抗原 See all LRRC1 products
    LRRC1 (Leucine Rich Repeat Containing 1 (LRRC1))
    抗原表位
    • 3
    • 1
    • 1
    C-Term
    适用
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 7
    克隆类型
    • 7
    多克隆
    标记
    • 7
    This LRRC1 antibody is un-conjugated
    应用范围
    • 6
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects LRRC1.
    交叉反应 (详细)
    Species reactivity (tested):Human
    纯化方法
    Peptide affinity chromatography
    免疫原
    Lano antibody was raised against a peptide corresponding to 15 amino acids near the carboxy terminus of human Lano.
    亚型
    IgG
  • 应用备注
    ELISA. Western blot: 1 -2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    LRRC1 (Leucine Rich Repeat Containing 1 (LRRC1))
    别名
    LRRC1 (LRRC1 产品)
    别名
    LRRC1 antibody, LANO antibody, dJ523E19.1 antibody, A430093J20Rik antibody, AU016091 antibody, D030059I21 antibody, mKIAA4018 antibody, leucine rich repeat containing 1 antibody, Lrrc1 antibody, LRRC1 antibody
    背景
    Lano is a member of the LAP (leucine-rich repeats and PDZ) family of proteins that also includes Densin-180, Erbin, and hScribble (1). The LAP proteins generally contain multiple leucine-rich repeat (LRR) domains which serve to target them to the basolateral membrane of epithelial cells (2). Lano is unique in that it alone does not possess one or more PDZ (PSD95/DLG/ZO-1) domains as do the other members of the LAP family. However, it can bind to the PDZ domain of Erbin in addition to those of membrane-associated and guanylate kinase (MAGUK) proteins which regulate adhesion and plasticity at cell junctions (1,3). It has been suggested that it is through these interaction that these LAP proteins participate in the maintenance of proper embryonic development and integrity of epithelial tissues (4,5).Synonyms: LANO, LANO adapter protein, LAP and no PDZ protein, LRRC1, Leucine-rich repeat-containing protein 1
    基因ID
    55227
    UniProt
    Q9BTT6
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