LARP1 抗体 (AA 123-401) (Biotin)
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北京 101111
Quick Overview for LARP1 抗体 (AA 123-401) (Biotin) (ABIN8004863)
抗原
See all LARP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 123-401
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原理
- Anti-LARP1 Antibody Biotin Conjugated
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human LARP1 recombinant protein (Position: K123-E401).
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亚型
- IgG
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anti-La Ribonucleoprotein Domain Family, Member 1 (LARP1) antibody
LARP1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-La Ribonucleoprotein Domain Family, Member 1 (LARP1) (AA 123-401) antibodyLARP1 适用: 人, 小鼠 WB, ELISA, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-La Ribonucleoprotein Domain Family, Member 1 (LARP1) (AA 1-1019) antibodyLARP1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-La Ribonucleoprotein Domain Family, Member 1 (LARP1) (AA 275-325) antibodyLARP1 适用: 人 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-La Ribonucleoprotein Domain Family, Member 1 (LARP1) (AA 575-625) antibodyLARP1 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
anti-La Ribonucleoprotein Domain Family, Member 1 (LARP1) (AA 36-85) antibodyLARP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-La Ribonucleoprotein Domain Family, Member 1 (LARP1) (AA 107-156) antibodyLARP1 适用: 人, 兔, Cow, 犬, 豚鼠, 马, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-La Ribonucleoprotein Domain Family, Member 1 (LARP1) (AA 575-625) antibodyLARP1 适用: 人 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- LARP1 (La Ribonucleoprotein Domain Family, Member 1 (LARP1))
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别名
- LARP1
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背景
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Background: La-related protein 1 (LARP1) is a 150 kDa protein that in humans is encoded by the LARP1 gene. La-related protein 1 (LARP1) is a ubiquitously expressed RNA binding protein that promotes both global and specific mRNA translation in cells. LARP1 belongs to the La-related protein family and contains two RNA binding domains, a La motif (LAM), and a neighboring RNA recognition motif-like (RRM-L) domain. Research studies indicate that LARP1 acts downstream of mTORC1 to facilitate cell proliferation and growth by promoting global mRNA translation and translation of mRNAs containing a 5'Terminal Oligo-Pyrimidine (5'TOP) motif, which code for translational machinery components. At the molecular level, LARP1 associates with 5'TOP mRNAs and multiple translation machinery components to positively regulate translation. Additional studies show that LARP1 expression is upregulated in hepatocellular carcinoma (HCC) patients and that high LARP1 expression in HCC negatively correlates with survival rate.
Gene Full Name: La ribonucleoprotein 1, translational regulator
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基因ID
- 23367
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UniProt
- Q6PKG0
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途径
- SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
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