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KIT Ligand 抗体 (N-Term)

This 兔 多克隆 antibody specifically detects KIT Ligand in WB 和 IHC. It exhibits reactivity toward 人.
产品编号 ABIN8004653
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for KIT Ligand 抗体 (N-Term) (ABIN8004653)

抗原

See all KIT Ligand (KITLG) 抗体
KIT Ligand (KITLG)

适用

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宿主

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克隆类型

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多克隆

标记

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This KIT Ligand antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)

质量等级

Carrier-free
  • 抗原表位

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    N-Term

    原理

    Anti-SCF/KITLG Antibody

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-SCF/KITLG Antibody. Tested in IHC, WB applications. This antibody reacts with Human.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human SCF.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, HumanWestern blot, 0.1-0.5 μg/mL, Human

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    储存液

    Sodium azide, Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    KIT Ligand (KITLG)

    别名

    KITLG

    背景

    Background: Stem Cell Factor (also known as SCF, kit-ligand, KL, or steel factor) is a cytokine that binds to the c-Kit receptor (CD117). SCF can exist both as a transmembrane protein and a soluble protein. SCF is localized to the long arm of human chromosome 12, between 12q14.3 and 12qter. SCF plays a role in the regulation of HSCs in the stem cell niche in the bone marrow. SCF has been shown to increase the survival of HSCs in vitro and contributes to the self renewal and maintenance of HSCs in-vivo. HSCs at all stages of development express the same levels of the receptor for SCF (c-Kit). The stromal cells that surround HSCs are a component of the stem cell niche, and they release a number of ligands, including SCF.

    Gene Full Name: KIT ligand

    Sequence Similarities: Belongs to the SCF family.

    分子量

    18.4 kDa

    基因ID

    4254

    UniProt

    P21583

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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