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KIT Ligand 抗体 (N-Term) (Biotin)

The Biotin-conjugated 兔 多克隆 anti-KIT Ligand antibody (ABIN8004643) specifically detects KIT Ligand in WB, IHC 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN8004643
发货至: 中国
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Quick Overview for KIT Ligand 抗体 (N-Term) (Biotin) (ABIN8004643)

抗原

See all KIT Ligand (KITLG) 抗体
KIT Ligand (KITLG)

适用

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宿主

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克隆类型

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多克隆

标记

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This KIT Ligand antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
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    N-Term

    原理

    Anti-SCF/KITLG Antibody Biotin Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human SCF.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    KIT Ligand (KITLG)

    别名

    KITLG

    背景

    Background: Stem Cell Factor (also known as SCF, kit-ligand, KL, or steel factor) is a cytokine that binds to the c-Kit receptor (CD117). SCF can exist both as a transmembrane protein and a soluble protein. SCF is localized to the long arm of human chromosome 12, between 12q14.3 and 12qter. SCF plays a role in the regulation of HSCs in the stem cell niche in the bone marrow. SCF has been shown to increase the survival of HSCs in vitro and contributes to the self renewal and maintenance of HSCs in-vivo. HSCs at all stages of development express the same levels of the receptor for SCF (c-Kit). The stromal cells that surround HSCs are a component of the stem cell niche, and they release a number of ligands, including SCF.

    Gene Full Name: KIT ligand

    Sequence Similarities: Belongs to the SCF family.

    基因ID

    4254

    UniProt

    P21583

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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