Kallikrein 6 抗体 (AA 22-244) (Biotin)
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Quick Overview for Kallikrein 6 抗体 (AA 22-244) (Biotin) (ABIN8003894)
抗原
See all Kallikrein 6 (KLK6) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 22-244
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原理
- Anti-Kallikrein 6/KLK6 Antibody Biotin Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human Kallikrein 6 recombinant protein (Position: L22-K244).
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亚型
- IgG
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anti-Kallikrein 6 (KLK6) (AA 17-244) antibody
KLK6 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 6 (KLK6) (AA 91-190) antibodyKLK6 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4A10 unconjugated
anti-Kallikrein 6 (KLK6) (AA 22-244) antibodyKLK6 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 6 (KLK6) (AA 1-30), (N-Term) antibodyKLK6 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB6114 unconjugated
anti-Kallikrein 6 (KLK6) (AA 217-244) antibodyKLK6 适用: 大鼠 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 6 (KLK6) (AA 126-156) antibodyKLK6 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB6116 unconjugated
anti-Kallikrein 6 (KLK6) (Internal Region) antibodyVerified KLK6 适用: 人 IHC, ELISA, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-Kallikrein 6 (KLK6) (AA 74-123) antibodyKLK6 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 6 (KLK6) (C-Term) antibodyKLK6 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 6 (KLK6) (C-Term) antibodyKLK6 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- Kallikrein 6 (KLK6)
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别名
- KLK6
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背景
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Background: KLK6 (Kallikrein-related peptidase 6), also called KALLIKREIN 6, NEUROSIN, PROTEASE M, ZYME or PRSS9, is a protein that in humans is encoded by the KLK6 gene. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. Northern blot analysis revealed that the PRSS9 mRNA was expressed in several primary tumors and cell lines from mammary, prostate, and ovarian cancers, but was not detected in any metastases of these cancers. The KLK6 gene is mapped on 19q13.41. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Upon cellular stress, neurosin was released from mitochondria to the cytosol, which resulted in the increase of degraded alpha-synuclein species. Neurosin may play a significant role in physiologic alpha-synuclein degradation and also in the pathogenesis of synucleinopathies.
Gene Full Name: kallikrein related peptidase 6
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基因ID
- 5653
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UniProt
- Q92876
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途径
- Complement System, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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