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JAK3 抗体 (AA 406-661) (Fluoro550)

This 兔 多克隆 antibody specifically detects JAK3 in FACS. It exhibits reactivity toward 人.
产品编号 ABIN8003600
发货至: 中国
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Quick Overview for JAK3 抗体 (AA 406-661) (Fluoro550) (ABIN8003600)

抗原

See all JAK3 抗体
JAK3 (Janus Kinase 3 (JAK3))

适用

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宿主

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克隆类型

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多克隆

标记

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This JAK3 antibody is conjugated to Fluoro550

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 406-661

    原理

    Anti-JAK3 Antibody Fluoro550 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human JAK3 recombinant protein (Position: Q406-D661).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    JAK3 (Janus Kinase 3 (JAK3))

    别名

    JAK3

    背景

    Background: Tyrosine-protein kinase JAK3 is an enzyme that in humans is encoded by the JAK3 gene. It is mapped to 19p13.11. The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).

    Gene Full Name: Janus kinase 3

    基因ID

    3718

    UniProt

    P52333

    途径

    JAK/STAT Signaling, RTK signaling, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus, Activated T Cell Proliferation, Unfolded Protein Response
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