JAG2 抗体 (AA 22-1153)
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Quick Overview for JAG2 抗体 (AA 22-1153) (ABIN8003585)
抗原
See all JAG2 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 22-1153
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原理
- Anti-Jagged 2/JAG2 Antibody
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交叉反应 (详细)
- No cross reactivity with other proteins.
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预测反应
- Human JAG2 shares 91.1%,91% amino acid (aa) sequence identity with mouse,rat JAG2,respectively.
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产品特性
- Anti-Jagged 2/JAG2 Antibody. Tested in ELISA, WB applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Jagged 2/JAG2 recombinant protein (Position: Q22-N1153). Human JAG2 shares 91.1% and 91% amino acid (aa) sequence identity with mouse and rat JAG2, respectively.
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亚型
- IgG
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- JAG2 (Jagged 2 (JAG2))
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别名
- JAG2
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背景
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Background: Protein jagged-2, also known as SER2, is a protein that in humans is encoded by the JAG2 gene. It is mapped to 14q32.33. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Notch ligands Delta1 and JAG2 are subject to presenilin-dependent, intramembranous gamma-secretase processing, resulting in the production of soluble intracellular derivatives. JAG2 can promote the growth and dissemination of uveal melanoma cells.
Gene Full Name: jagged canonical Notch ligand 2
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分子量
- 130 kDa
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基因ID
- 3714
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UniProt
- Q9Y219
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途径
- Notch Signaling, Sensory Perception of Sound
抗原
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