IFT74 抗体 (AA 1-375)
Our Local Distributor
北京 101111
Quick Overview for IFT74 抗体 (AA 1-375) (ABIN8003145)
抗原
See all IFT74 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
-
-
抗原表位
- AA 1-375
-
原理
- Anti-IFT74 Antibody
-
交叉反应 (详细)
- No cross reactivity with other proteins.
-
预测反应
- Human PELI3 shares 90.1% amino acid (aa) sequence identity with mouse PELI3.
-
产品特性
- Anti-IFT74 Antibody. Tested in ELISA, IHC, WB, Flow Cytometry applications. This antibody reacts with Human, Monkey, Mouse, Rat.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human PELI3 recombinant protein (Position: M1-R375). Human PELI3 shares 90.1% amino acid (aa) sequence identity with mouse PELI3.
-
亚型
- IgG
-
-
-
-
应用备注
- Western blot, 0.25-0.5 μg/mL, Human, Monkey, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
-
-
- IFT74 (Intraflagellar Transport Protein 74 Homolog (IFT74))
-
别名
- IFT74
-
背景
-
Background: Intraflagellar transport protein 74 homolog (IFT74), also known as coiled-coil domain-containing protein 2 (CCDC2) and capillary morphogenesis gene 1 protein (CMG1), is a protein that in humans is encoded by the IFT74 gene. This gene encodes a core intraflagellar transport (IFT) protein which belongs to a multi-protein complex involved in the transport of ciliary proteins along axonemal microtubules. IFT proteins are found at the base of the cilium as well as inside the cilium, where they assemble into long arrays between the ciliary base and tip. This protein, together with intraflagellar transport protein 81, binds and transports tubulin within cilia and is required for ciliogenesis. Naturally occurring mutations in this gene are associated with amyotrophic lateral sclerosis--frontotemporal dementia and Bardet-Biedl Syndrome.
Gene Full Name: intraflagellar transport 74
-
分子量
- 69 kDa
-
基因ID
- 80173
-
UniProt
- Q96LB3
-
途径
- Hedgehog Signaling, Chromatin Binding
抗原
-